Evidence map›Paper›PMID 21244013›Full record

ArticleInorganic chemistry2011

Linear correlation between 1H and 13C chemical shifts of ferriheme proteins and model ferrihemes.

Fei Yang, Tatiana K Shokhireva, F Ann Walker

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Inorganic chemistry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. NMR investigations of nitrophorin 2 belt side chain effects on heme orientation and seating of native N-terminus NP2 and NP2(D1A).Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Fei YangDepartment of Chemistry and Biochemistry, The University of Arizona, P.O. Box 210041, Tucson, Arizona 85721-0041, United States.
Tatiana K Shokhireva
F Ann Walker

Funding

NITRIC OXIDE INTERACTION WITH INSECT NITROPHORINSR01HL054826 · NHLBI · UNIVERSITY OF ARIZONA · PI WALKER, FRANCES ANN · 1995 to 2012
$3.5M
MODELS OF THE CYTOCHROMESR01DK031038 · NIDDK · UNIVERSITY OF ARIZONA · PI WALKER, FRANCES ANN · 1986 to 2005
$1.6M
Models of the CytochromesR56DK031038 · NIDDK · UNIVERSITY OF ARIZONA · PI WALKER, FRANCES ANN · 2006 to 2006
$99k
NHLBI NIH HHS R01 HL054826NIDDK NIH HHS DK031038NIDDK NIH HHS R01 DK031038NIDDK NIH HHS R56 DK031038
6 · The paper itself

Abstract

The (1)H{(13)C} HMQC experiment at natural-abundance (13)C provides a very useful way of determining not only (1)H but also (13)C chemical shifts of most heme substituents, without isotopic labeling of the hemin. This is true both in model low-spin ferriheme complexes and in low-spin ferriheme proteins, even when the proton resonances are buried in the protein diamagnetic region, because the carbon shifts are much larger than the proton shifts. In addition, in many cases, the protohemin methyl cross peaks are fairly linearly related to each other, with the slope of the correlation, δ(C)/δ(H), being approximately -2.0 for most low-spin ferriheme proteins. The reasons why this should be the case, and when it is not, are discussed.

Indexed as

Models, ChemicalCarbon IsotopesHemeproteinsHeminHydrogenIsotope LabelingMagnetic Resonance SpectroscopyProtonsCarbon IsotopesHemeproteinsHeminHydrogenProtons

Identifiers

PMID21244013
PMCPMC3079238

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.