ArticleFunctional & integrative genomics2011
A nonsense mutation in a putative sulphate transporter gene results in low phytic acid in barley.
Article in Functional & integrative genomics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 45 citations in OpenAlex.
- Identification and Expression Analysis of Sulfate Transporter Genes Family and Function Analysis ofInternational journal of molecular sciences · 2024Article
- Identifying genes associated with abiotic stress tolerance suitable for CRISPR/Cas9 editing in upland rice cultivars adapted to acid soils.Plant direct · 2022Article
- Genotypic Differences in the Effect of P Fertilization on Phytic Acid Content in Rice Grain.Plants (Basel, Switzerland) · 2020Article
- Article
- Phytic Acid and Transporters: What Can We Learn fromPlants (Basel, Switzerland) · 2020Review
- Contribution of External and Internal Phosphorus Sources to Grain P Loading in Durum Wheat (Frontiers in plant science · 2020Article
- Plant Sulfate Transporters in the Low Phytic Acid Network: Some Educated Guesses.Plants (Basel, Switzerland) · 2019Article
- Novel allelic variant of Lpa1 gene associated with a significant reduction in seed phytic acid content in rice (Oryza sativa L.).PloS one · 2019Article
- RNAi-Mediated Downregulation of Inositol Pentakisphosphate Kinase (Frontiers in plant science · 2018Article
- Phosphorus remobilization from rice flag leaves during grain filling: an RNA-seq study.Plant biotechnology journal · 2017Article
- A Substantial Fraction of Barley (Hordeum vulgare L.) Low Phytic Acid Mutations Have Little or No Effect on Yield across Diverse Production Environments.Plants (Basel, Switzerland) · 2015Article
- Overexpression of a Gene Involved in Phytic Acid Biosynthesis Substantially Increases Phytic Acid and Total Phosphorus in Rice Seeds.Plants (Basel, Switzerland) · 2015Article
- Improving phosphorus efficiency in cereal crops: Is breeding for reduced grain phosphorus concentration part of the solution?Frontiers in plant science · 2013Article
- STAS domain structure and function.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology · 2011Review
- The SLC26 gene family of anion transporters and channels.Molecular aspects of medicineReview
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Low phytic acid grains can provide a solution to dietary micronutrient deficiency and environmental pollution. A low phytic acid 1-1 (lpa1-1) barley mutant was identified using forward genetics and the mutant gene was mapped to chromosome 2HL. Comparative genomic analysis revealed that the lpa1-1 gene was located in the syntenic region of the rice Os-lpa-MH86-1 gene on chromosome 4. The gene ortholog of rice Os-lpa-MH86-1 (designated as HvST) was isolated from barley using polymerase chain reaction and mapped to chromosome 2HL in a doubled haploid population of Clipper×Sahara. The results demonstrate the collinearity between the rice Os-lpa-MH86-1 gene and the barley lpa1-1 region. Sequence analysis of HvST revealed a single base pair substitution (C→T transition) in the last exon of the gene in lpa1-1 (M422), which resulted in a nonsense mutation. These results will facilitate our understanding of the molecular mechanisms controlling the low phytic acid phenotype and assist in the development of a diagnostic marker for the selection of the lpa1-1 gene in barley.
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