Evidence map›Paper›PMID 21243472›Full record

ReviewCurrent topics in behavioral neurosciences2011

Reward and neurocomputational processes.

Guido K W Frank

Abstract readReview
In one paragraph

Review in Current topics in behavioral neurosciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Toward valid and reliable brain imaging results in eating disorders.The International journal of eating disorders · 2018
    Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Guido K W FrankDepartment of Psychiatry, Developmental Brain Research Program, University of Colorado Denver, The Children's Hospital, Gary Pavilion A036/B-130, 13123 East 16th Avenue, Aurora, CO 80045, USA. Guido.Frank@ucdenver.edu
University of Colorado Denver · US

Funding

Brain Reward-Pathway Function and Neurocomputational Modeling in Anorexia NervosaK23MH080135 · NIMH · UNIVERSITY OF COLORADO DENVER · PI FRANK, GUIDO KW · 2008 to 2012
$840k
NIMH NIH HHS K23 MH080135
6 · The paper itself

Abstract

The neurobiology of eating disorders (EDs) is largely unknown. However, brain imaging studies over the past decade have identified neurotransmitter alterations that could be part of dysfunctional behavior characteristics of EDs. In this chapter we focus on a specific behavioral construct, the brain reward system, and demonstrate a functional brain imaging approach toward identifying dopamine function in anorexia nervosa (AN). We demonstrate how human brain reward activation can be used in a translational approach to test whether computer models, based on basic science research, can predict expected in vivo reward system activation, and how such an approach can identify specific biologic alterations in a psychiatric population.

Indexed as

Computer SimulationFeeding and Eating DisordersModels, NeurologicalRewardBrainHumansNeural PathwaysNeuroimaging

Identifiers

PMID21243472
PMCPMC3722417
OpenAlexW1529619526

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.