SynthesisInternational orthopaedics2011
Reamer-irrigator-aspirator indications and clinical results: a systematic review.
Synthesis in International orthopaedics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 3 syntheses or guidelines pooled it, 142 citations in OpenAlex.
- Complications associated using the reamer-irrigator -aspirator (RIA) system: a systematic review and meta-analysis.Archives of orthopaedic and trauma surgery · 2023Pooled it
- Outcomes and complications of the reamer irrigator aspirator versus traditional iliac crest bone graft harvesting: a systematic review and meta-analysis.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2021Pooled it
- Autologous bone graft in the treatment of post-traumatic bone defects: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2016Pooled it
- Article
- A review of the Masquelet technique in the treatment of lower limb critical-size bone defects.Annals of the Royal College of Surgeons of England · 2025Review
- Complications of Reamer-Irrigator-Aspirator System in Pediatric Orthopedic Surgery-Case Series and Scoping Review.Children (Basel, Switzerland) · 2025Review
- The Genetic and Biological Basis of Pseudoarthrosis in Fractures: Current Understanding and Future Directions.Diseases (Basel, Switzerland) · 2025Review
- Irrigation of the intramedullary channel improves outcome of DAIR in a sheep model.NPJ biofilms and microbiomes · 2025Article
- Secondary removal of intramedullary metal debris from a defective Reamer-Irrigator-Aspirator (RIA) reamer head: A case report.Trauma case reports · 2024Article
- Masquelet Technique Combined with Ilizarov External Fixator, Reamer-irrigator-aspirator, and Flap Transplantation in an Open Tibial Fracture: A Case Report.Journal of orthopaedic case reports · 2024Article
- In vivo study to assess fat embolism resulting from the Reamer-Irrigator-Aspirator 2 system compared to a novel aspirator-based concept for intramedullary bone graft harvesting.Archives of orthopaedic and trauma surgery · 2024Article
- Femoral nailing associated with bone marrow emboli in pigs induced a specific increase in blood IL-6 and broad inflammatory responses in the heart and lungs.Frontiers in immunology · 2024Article
- Acute toxic shock syndrome associated with intra-operative debridement and instrumentation removal for chronic osteomyelitis: A report of two cases.Trauma case reports · 2023Article
- Current concepts of bone grafting in trauma surgery.Journal of clinical orthopaedics and trauma · 2023Article
- What Is the Best Treatment of the Femoral Shaft Nonunion after Intramedullary Nailing? A Systematic Review.Life (Basel, Switzerland) · 2023Review
- Biological aspects to enhance fracture healing.EFORT open reviews · 2023Review
- Long-term posterolateral spinal fusion in rabbits induced by rhBMP6 applied in autologous blood coagulum with synthetic ceramics.Scientific reports · 2022Article
- Fusion Revision Surgery With Reamer-Irrigator-Aspirator to Harvest Autograft After Spinal Pseudarthrosis.Cureus · 2022Article
- Atrophic pseudarthrosis of humeral diaphyseal fractures: medico-legal implications and methodological analysis of the evaluation.Acta bio-medica : Atenei Parmensis · 2022Article
- Safety and efficacy of a novel retrograde route for femoral bone graft harvesting by Reamer-Irrigator-Aspirator: a pilot study on 24 patients.Patient safety in surgery · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe 'reamer-irrigator-aspirator' (RIA) is an innovation developed to reduce fat embolism (FE) and thermal necrosis (TN) that can occur during reaming/nailing of long-bone fractures. Since its inception its indications have expanded to include the treatment of long-bone osteomyelitis and as a harvester of bone graft/mesenchymal stem cells (MSCs).
methodsThis study involved a systematic review, via Pubmed® and Google Scholar®, of English language sources (nine non-clinical studies, seven clinical studies and seven case reports) using the keywords: 'reamer', 'irrigator', 'aspirator' (1st May 2010). Sources were reviewed with reference to the RIAs efficacy in (1) preventing FE/TN, (2) treating long-bone osteomyelitis, (3) harvesting bone graft/MSCs, and (4) operating safely. Experimental data supports the use of the RIA in preventing FE and TN, however, there is a paucity of clinical data.
conclusionsThe RIA is a reliable method in achieving high volumes of bone graft/MSCs, and high union rates are reported when using RIA bone-fragments to treat non-unions. Evidence suggests possible effectiveness in treating long-bone osteomyelitis. The RIA appears relatively safe, with a low rate of morbidity provided a meticulous technique is used. When complications occur they respond well to conventional techniques. The RIA demands further investigation especially with respect to the optimal application of MSCs for bone repair strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.