Evidence map›Paper›PMID 21243344›Full record

ArticleEuropean journal of clinical pharmacology2011

Suspected adverse reactions associated with herbal products used for weight loss: a case series reported to the Italian National Institute of Health.

Annabella Vitalone, Francesca Menniti-Ippolito, Paola Angela Moro, Fabio Firenzuoli, Roberto Raschetti, Gabriela Mazzanti

Abstract read
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In one paragraph

Article in European journal of clinical pharmacology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
11.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.

  1. Pooled it
  2. Review
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  11. Review
  12. Article
  13. Herbal hepatotoxicity: a hidden epidemic.Internal and emergency medicine · 2013
    Review
  14. Abuse and Misuse of Selected Dietary Supplements Among Adolescents: a Look at Poison Center Data.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Annabella VitaloneDepartment of Physiology and Pharmacology V. Erspamer, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy. annabella.vitalone@uniroma1.it
Francesca Menniti-Ippolito
Paola Angela Moro
Fabio Firenzuoli
Roberto Raschetti
Gabriela Mazzanti
National Centre for Disease Prevention and Control · ITSapienza University of Rome · ITOspedale Maggiore · ITOspedale San Giuseppe · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to describe suspected adverse reactions (ARs) associated with herbal products used for weight control in Italy.

methodsSpontaneous reports of suspected ARs associated with herbal products used for weight control were collected by the Italian National Institute of Health (April 2002 to June 2010), and the causality assessment was performed.

resultsForty-six of the suspected ARs were associated with herbal products used for weight control. Women were involved in 85% of the reports. The reactions affected mainly the cardiovascular system, the skin, the digestive system, the central nervous system, and the liver. A large proportion of ARs were serious. In more than half of the suspected ARs, the use of other therapies (herbs and/or drugs) was reported, while concomitant conditions were present in 22% of the reports.

conclusionsThe use of herbal dietary supplements for weight loss is associated with several ARs. Considering the risk/benefit ratio, consumers should pay attention when using these products.

Indexed as

AdolescentAdultAdverse Drug Reaction Reporting SystemsDatabases, FactualFemaleHumansItalyMaleMiddle AgedPhytotherapyPlant PreparationsWeight LossYoung AdultPlant Preparations

Identifiers

PMID21243344
OpenAlexW1992716737

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.