Evidence map›Paper›PMID 21243026›Full record

ArticleBone marrow transplantation2011

Vitamin D status among long-term survivors of hematopoietic cell transplantation.

K Robien, L G Strayer, N Majhail, D Lazovich, K S Baker, A R Smith, D A Mulrooney, L J Burns

Abstract read
In one paragraph

Article in Bone marrow transplantation, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Vitamin D Deficiency in Testicular Cancer Survivors: A Systematic Review.International journal of molecular sciences · 2021
    Pooled it
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  6. Serum vitamin d levels predict hospital-free days in outpatient allogeneic stem cell transplantation survivors: implications for long-term health outcomes.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  19. Long-term follow-up after allogeneic stem cell transplantation.Deutsches Arzteblatt international · 2015
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

K RobienDivision of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis, MN 55454, USA. robie004@umn.edu
L G Strayer
N Majhail
D Lazovich
K S Baker
A R Smith
D A Mulrooney
L J Burns

Funding

Genetic Variation in Vitamin D Metabolism and BMT OutcomesR21CA135180 · NCI · UNIVERSITY OF MINNESOTA · PI ROBIEN, KIMBERLY Z · 2008 to 2009
$340k
NCI NIH HHS R21 CA135180
6 · The paper itself

Abstract

Little is known about serum vitamin D levels following hematopoietic cell transplantation (HCT). Patients are instructed to avoid sun exposure because of an increased risk of skin cancers. Altered gastrointestinal absorptive capacity as a result of GVHD, bile acid or pancreatic enzyme insufficiency or bacterial overgrowth may lead to difficulty in absorbing the fat-soluble vitamin D. This study was undertaken to determine the prevalence of serum 25-hydroxyvitamin D (25(OH)D) deficiency, and factors associated with 25(OH)D deficiency, among children and adults who were at least 1 year following HCT. A total of 95 participants (54 males and 41 females) completed a questionnaire on usual diet and lifestyle, and provided a blood sample for 25(OH)D determinations between November 2008 and July 2009. The majority of participants had serum 25(OH)D levels ≥75 nmol/L (n=62, 65%), 23 had insufficient levels (50-75 nmol/L) and 10 participants were deficient (<50 nmol/L). The majority of participants reported regular use of vitamin D supplements (n=58, 61%). Prednisone use was significantly inversely associated with serum 25(OH)D concentrations. Total vitamin D intake was the strongest single predictor of 25(OH)D concentrations. These findings suggest that 400-600 IU vitamin D per day appears to be required to achieve optimal serum 25(OH)D concentrations following HCT.

Indexed as

AdolescentAdultAgedBody Mass IndexBone Marrow TransplantationChildChild, PreschoolDietary SupplementsFemaleHumansMaleMiddle AgedPilot ProjectsPrednisoneSunlightSurvivors25-hydroxyvitamin DPrednisoneVitamin D

Identifiers

PMID21243026
PMCPMC3131431

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.