ReviewNature reviews. Urology2011
The DABBEC phenotyping system: towards a mechanistic understanding of CP/CPPS.
Review in Nature reviews. Urology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00672087 (Diagnostic Challenges in IC), which is not on this map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Diagnostic Challenges in IC (and Male CPPS)
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Classification systems for chronic pelvic pain in males: a systematic review.BJU international · 2025Pooled it
- Reproducible Microstructural Changes in the Brain Associated With the Presence and Severity of Urologic Chronic Pelvic Pain Syndrome (UCPPS): A 3-Year Longitudinal Diffusion Tensor Imaging Study From the MAPP Network.The journal of pain · 2023Article
- Urologic chronic pelvic pain syndrome: insights from the MAPP Research Network.Nature reviews. Urology · 2019Review
- Article
- Article
- Physical activity and chronic prostatitis/chronic pelvic pain syndrome.Medicine and science in sports and exercise · 2015Article
- Reliability of superficial male pelvic floor structural measurements using linear-array transperineal sonography.Ultrasound in medicine & biology · 2015Article
- Altered resting state neuromotor connectivity in men with chronic prostatitis/chronic pelvic pain syndrome: A MAPP: Research Network Neuroimaging Study.NeuroImage. Clinical · 2015Article
- Article
- Chronic Fatigue Syndrome: The Current Status and Future Potentials of Emerging Biomarkers.Fatigue : biomedicine, health & behavior · 2014Article
- Pain, catastrophizing, and depression in chronic prostatitis/chronic pelvic pain syndrome.International neurourology journal · 2013Article
- Transperineal Sonography Evaluation of Muscles and Vascularity in the Male Pelvic Floor.Journal of diagnostic medical sonography : JDMS · 2013Article
- NGF - the TrkA to successful pain treatment.Journal of pain research · 2012Article
- The role of phenotyping in chronic prostatitis/chronic pelvic pain syndrome.Current urology reports · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is an urgent need to elucidate the mechanistic basis of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), as the current methods of symptom-based diagnosis and treatment have failed. Here, we propose a phenotyping system that bridges the gap between the symptom-based diagnosis and treatment of the present and the mechanistic approach of the future. Our phenotyping system uses the Chronic Prostatitis Collaborative Research Network (CPCRN)-recommended algorithm in combination with the NIH Chronic Prostatitis Symptom Index (NIH-CPSI) as a basis for diagnosis, while incorporating novel domains for quantitative assessment and stratification of CP/CPPS patients. We believe this novel system will serve to help advance our understanding of the roles of the patient's genome and proteome in the etiology of CP/CPPS. We predict that, as we begin to understand the mechanistic basis of CP/CPPS pathology and progression, we will develop specific treatments that will aim to cure the disease, rather than merely quell the symptoms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.