ReviewCurrent opinion in HIV and AIDS2011
Simian immunodeficiency virus macaque models of HIV latency.
Review in Current opinion in HIV and AIDS, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 26 citations in OpenAlex.
- Interactions between long-acting antiretrovirals and opioids: a call for clinical awareness.Clinical microbiology reviews · 2026Review
- Microphysiological model reveals the promise of memory-like natural killer cell immunotherapy for HIVNature communications · 2023Article
- Opioid abuse and SIV infection in non-human primates.Journal of neurovirology · 2023Review
- Psychosocial Stress Alters the Immune Response and Results in Higher Viral Load During Acute Simian Immunodeficiency Virus Infection in a Pigtailed Macaque Model of Human Immunodeficiency Virus.The Journal of infectious diseases · 2021Article
- Review
- HIV latency reversal research and the potential effects on the central nervous system: is concern warranted?Journal of the International AIDS Society · 2016Article
- Enhanced antiretroviral therapy in rhesus macaques improves RT-SHIV viral decay kinetics.Antimicrobial agents and chemotherapy · 2014Article
- HIV-1 envelope-receptor interactions required for macrophage infection and implications for current HIV-1 cure strategies.Journal of leukocyte biology · 2014Review
- Cellular and molecular mechanisms involved in the establishment of HIV-1 latency.Retrovirology · 2013Review
- Article
- Developing strategies for HIV-1 eradication.Trends in immunology · 2012Review
- Therapeutic imprinting of the immune system: towards a remission of AIDS in primates?Retrovirology · 2012Article
- Targeted DNA mutagenesis for the cure of chronic viral infections.Journal of virology · 2012Review
- The non-human primate model of tuberculosis.Journal of medical primatology · 2012Review
- HIV latency: experimental systems and molecular models.FEMS microbiology reviews · 2012Review
- A highly intensified ART regimen induces long-term viral suppression and restriction of the viral reservoir in a simian AIDS model.PLoS pathogens · 2012Article
- Nonhuman primate models for HIV cure research.PLoS pathogens · 2012Article
- Generation of HIV latency in humanized BLT mice.Journal of virology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
purpose of reviewThis review will focus on recent developments in several nonhuman primate models of AIDS. These models are being used to address viral latency and persistence during antiretroviral therapy in studies that are not feasible in humans. RECENT
findingsFurther characterization of the various macaque models of AIDS has demonstrated that several aspects of viral persistence during antiretroviral therapy model HIV-1 infection in humans, including viral decay kinetics. Widespread distribution of viral RNA and viral DNA has been detected in many tissue organs. In addition, the brain has been identified as a site of persistent viral DNA. SUMMARY: The macaque models of AIDS are well suited for addressing viral persistence during antiretroviral therapy, including viral latency, residual replication, and tissue organ distribution.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.