The acetaminophen enigma in asthma.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

13 citing papers in PubMed.

1. A Randomized Placebo Controlled Trial of Ibuprofen for Respiratory Syncytial Virus Infection in a Bovine Model.PloS one · 2016
   Trial
2. Randomised placebo-controlled study of the effect of paracetamol on asthma severity in adults.BMJ open · 2014
   Trial
3. A clinical and safety review of paracetamol and ibuprofen in children.Inflammopharmacology · 2017
   Review
4. Effects of Acetaminophen on Oxidant and Irritant Respiratory Tract Responses to Environmental Tobacco Smoke in Female Mice.Environmental health perspectives · 2016
   Article
5. Clinical pharmacology of paracetamol in neonates: a review.Current therapeutic research, clinical and experimental · 2015
   Review
6. Causal assessment of pharmaceutical treatments: why standards of evidence should not be the same for benefits and harms?Drug safety · 2015
   Article
7. A practical approach to the treatment of low-risk childhood fever.Drugs in R&D · 2014
   Review
8. Risk factors for eczema in infants born in Cuba: a population-based cross-sectional study.BMC dermatology · 2014
   Article
9. Safety vs. efficacy assessment of pharmaceuticals: Epistemological rationales and methods.Preventive medicine reports · 2014
   Article
10. Asthma management in sickle cell disease.BioMed research international · 2013
    Review
11. Update in asthma 2011.American journal of respiratory and critical care medicine · 2012
    Review
12. Decreased expression of acetaminophen-metabolizing enzymes and glutathione in asthmatic children after acetaminophen exposure.The Journal of allergy and clinical immunology · 2012
    Article
13. Prevalence and factors associated with adult bronchial asthma in Aseer region, Southwestern Saudi Arabia.Annals of thoracic medicine
    Article

Corrections and comments

• Comment on
  Acetaminophen use and risk of asthma, rhinoconjunctivitis, and eczema in adolescents: International Study of Asthma and Allergies in Childhood Phase Three.2011
• Comment on
  The role of acetaminophen and geohelminth infection on the incidence of wheeze and eczema: a longitudinal birth-cohort study.2011

Authors and funding

1 author.

Funding

Abstract

PubMed holds no abstract for this paper.

Indexed as