Evidence map›Paper›PMID 21242555›Full record

Trial reportAnnals of family medicine

Effect of preventive messages tailored to family history on health behaviors: the Family Healthware Impact Trial.

Mack T Ruffin, Donald E Nease, Ananda Sen, Wilson D Pace, Catharine Wang, Louise S Acheson, Wendy S Rubinstein, Suzanne O'Neill, Robert Gramling, Family History Impact Trial (FHITr) Group

Open access · diamondAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Annals of family medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed, 6 pooled it
12.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 6 syntheses or guidelines pooled it, 140 citations in OpenAlex.

  1. Pooled it
  2. mHealth education interventions in heart failure.The Cochrane database of systematic reviews · 2020
    Pooled it
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  7. Trial
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  9. User Perceptions and Reactions to an Online Cancer Risk Assessment Tool: a Process Evaluation of Cancer Risk Check.Journal of cancer education : the official journal of the American Association for Cancer Education · 2017
    Trial
  10. Let's Move Together.Health education & behavior : the official publication of the Society for Public Health Education · 2017
    Trial
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  15. A randomized, controlled trial to increase discussion of breast cancer in primary care.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2014
    Trial
  16. Trial
  17. Trial
  18. Family history assessment: impact on disease risk perceptions.American journal of preventive medicine · 2012
    Trial
  19. Clinical utility of family history for cancer screening and referral in primary care: a report from the Family Healthware Impact Trial.Genetics in medicine : official journal of the American College of Medical Genetics · 2011
    Trial
  20. Review

20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Mack T RuffinDepartment of Family Medicine, University of Michigan, Ann Arbor, MI, USA.
Donald E Nease
Ananda Sen
Wilson D Pace
Catharine Wang
Louise S Acheson
Wendy S Rubinstein
Suzanne O'Neill
Robert Gramling
Family History Impact Trial (FHITr) Group
University of Michigan · USAmerican Academy of Family Physicians · USBoston University · USCase Western Reserve University · USNorthShore University HealthSystem · USNorthwestern University · USUniversity of Rochester · US

Funding

Clinical and Translational Science Collaborative of ClevelandUL1TR000439 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI KONSTAN, MICHAEL W. · 2012 to 2016
$50.0M
Communication of Genetic and Environmental Risks in Colorectal Cancer PreventionK07CA131103 · NCI · FOX CHASE CANCER CENTER · PI WANG, CATHARINE · 2008 to 2012
$674k
THE 'GREAT'SYSTEM TO IDENTIFY FAMILIAL CANCER RISKK07CA086958 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI ACHESON, LOUISE SEYMOUR · 2000 to 2005
$656k
NCATS NIH HHS UL1 TR000439NCI NIH HHS K07CA086958NCI NIH HHS K07 CA131103
6 · The paper itself

Abstract

purposeWe wanted to determine the impact of automated family history assessment and tailored messages for coronary heart disease, stroke, diabetes, colorectal, breast, and ovarian cancer on preventive behaviors compared with a standard preventive message.

methodsThe study was a cluster-randomized clinical trial that included 41 primary care practices, the majority in the Midwest, using Family Healthware, a self-administered, Web-based tool that assesses familial risk for the diseases and provides personalized risk-tailored messages. Patients in the control group received an age- and sex-specific health message related to lifestyle and screening. Smoking cessation, fruit and vegetable intake, physical activity, aspirin use, blood pressure, and cholesterol and blood glucose screening were assessed at baseline and 6 months after the intervention.

resultsOf 4,248 participants, 3,344 (78%) completed the study. Participants were white (91%), female (70%), and insured (97%), and had a mean age of 50.6 years (range 35-65 years). Intervention participants were more likely to increase daily fruit and vegetable consumption from 5 or fewer servings a day to 5 or more servings a day (OR = 1.29; 95% confidence interval [CI], 1.05-1.58) and to increase physical activity (OR = 1.47; 95% CI, 1.08-1.98) to 5 to 6 times a week for 30 minutes or more a week. The absolute differences in proportion were 3% and 4%, respectively. Intervention participants were less likely to move from not having cholesterol screening in the last 5 years to having their cholesterol measured within 5 years (OR = 0.34; 95% CI, 0.17-0.67), with an absolute difference of 15%.

conclusionsMessages tailored to an individual's familial risk for 6 common diseases modestly increased self-reported physical activity and fruit and vegetable intake but reduced the likelihood of receiving cholesterol screening.

Indexed as

CommunicationHealth BehaviorInternetRisk Reduction BehaviorAdultAspirinBlood GlucoseBlood PressureBreast NeoplasmsCholesterolChronic DiseaseCoronary DiseaseDiabetes Mellitus, Type 2DietExerciseFemaleAspirinBlood GlucoseCholesterol

Identifiers

PMID21242555
PMCPMC3022039
OpenAlexW2162457334

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.