ArticleGenetics2011
Targeted introgression of a wheat stem rust resistance gene by DNA marker-assisted chromosome engineering.
Article in Genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.
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Who cites it
73 citing papers in PubMed, 153 citations in OpenAlex.
- Dissection of Fusarium head blight resistance in a modified nested association mapping panel of synthetic and bread wheat germplasm.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Development and Characterization of Wheat-Plants (Basel, Switzerland) · 2025Article
- Marker-assisted introgression and characterization of the ph1b mutant in modern US and Australian wheats.The plant genome · 2025Article
- Introgression of stem rust resistance gene Sr68 from Thinopyrum junceum into wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- The TaNHLP1-TaRACK1A module regulates tillering via abscisic acid signaling in wheat.Nature communications · 2025Article
- Genetic Dissection of Triple Rust Resistance (Leaf, Yellow, and Stem Rust) in Kenyan Wheat Cultivar, "Kasuku".Plants (Basel, Switzerland) · 2025Article
- Breaking the association between gametocidal gene(s) and leaf rust resistance gene (Molecular breeding : new strategies in plant improvement · 2024Article
- Enrichment and Diversification of the Wheat Genome via Alien Introgression.Plants (Basel, Switzerland) · 2024Review
- The genetics of Ug99 stem rust resistance in spring wheat variety 'Linkert'.Frontiers in plant science · 2024Article
- Linkage drag analysis in three Aegilops speltoides introgressions carrying Sr47 in modern durum and hard red spring wheat germplasm.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Article
- Wheat Genes Associated with Different Types of Resistance against Stem Rust (Pathogens (Basel, Switzerland) · 2022Review
- Haplotype variants of Sr46 in Aegilops tauschii, the diploid D genome progenitor of wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- Domestication of newly evolved hexaploid wheat-A journey of wild grass to cultivated wheat.Frontiers in genetics · 2022Review
- Transfer of theFrontiers in plant science · 2022Article
- The decreased expression of GW2 homologous genes contributed to the increased grain width and thousand‑grain weight in wheat-Dasypyrum villosum 6VS·6DL translocation lines.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Article
- An approach for high-resolution genetic mapping of distant wild relatives of bread wheat: example of fine mapping of Lr57 and Yr40 genes.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Article
- Genomic resources in plant breeding for sustainable agriculture.Journal of plant physiology · 2021Review
- Identification and Validation of High LD Hotspot Genomic Regions Harboring Stem Rust Resistant Genes on 1B, 2A (Frontiers in genetics · 2021Article
- Significance of the Diversification of Wheat Species for the Assembly and Functioning of the Root-Associated Microbiome.Frontiers in microbiology · 2021Review
13 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chromosome engineering is a useful strategy for transfer of alien genes from wild relatives into modern crops. However, this strategy has not been extensively used for alien gene introgression in most crops due to low efficiency of conventional cytogenetic techniques. Here, we report an improved scheme of chromosome engineering for efficient elimination of a large amount of goatgrass (Aegilops speltoides) chromatin surrounding Sr39, a gene that provides resistance to multiple stem rust races, including Ug99 (TTKSK) in wheat. The wheat ph1b mutation, which promotes meiotic pairing between homoeologous chromosomes, was employed to induce recombination between wheat chromosome 2B and goatgrass 2S chromatin using a backcross scheme favorable for inducing and detecting the homoeologous recombinants with small goatgrass chromosome segments. Forty recombinants with Sr39 with reduced surrounding goatgrass chromatin were quickly identified from 1048 backcross progenies through disease screening and molecular marker analysis. Four of the recombinants carrying Sr39 with a minimal amount of goatgrass chromatin (2.87-9.15% of the translocated chromosomes) were verified using genomic in situ hybridization. Approximately 97% of the goatgrass chromatin was eliminated in one of the recombinants, in which a tiny goatgrass chromosome segment containing Sr39 was retained in the wheat genome. Localization of the goatgrass chromatin in the recombinants led to rapid development of three molecular markers tightly linked to Sr39. The new wheat lines and markers provide useful resources for the ongoing global effort to combat Ug99. This study has demonstrated great potential of chromosome engineering in genome manipulation for plant improvement.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.