Evidence map›Paper›PMID 21241424›Full record

ReviewHPB : the official journal of the International Hepato Pancreato Biliary Association2011

Analytical review of diagnosis and treatment strategies for dominant bile duct strictures in patients with primary sclerosing cholangitis.

Murad Aljiffry, Paul D Renfrew, Mark J Walsh, Marie Laryea, Michele Molinari

Open access · bronzeAbstract readReview
In one paragraph

Review in HPB : the official journal of the International Hepato Pancreato Biliary Association, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

  1. Guideline
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Klatskin-Mimicking Lesions.Diagnostics (Basel, Switzerland) · 2021
    Review
  9. Article
  10. Article
  11. [Consensus on the diagnosis and management of primary sclerosing cholangitis (2015 version)].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2016
    Article
  12. What is the current role of endoscopy in primary sclerosing cholangitis?World journal of gastrointestinal endoscopy · 2015
    Article
  13. Review
  14. Article
  15. Review
  16. Management of primary sclerosing cholangitis: conventions and controversies.Canadian journal of gastroenterology = Journal canadien de gastroenterologie · 2012
    Review
  17. Primary sclerosing cholangitis: is any treatment worthwhile?Current gastroenterology reports · 2012
    Review
  18. Klatskin-like lesions.HPB surgery : a world journal of hepatic, pancreatic and biliary surgery · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Murad AljiffrySection of Hepatopancreaticobiliary and Transplant Surgery, McGill University Health Centre, Montreal, Canada.
Paul D Renfrew
Mark J Walsh
Marie Laryea
Michele Molinari
Dalhousie University · CAQueen Elizabeth II Health Sciences Centre · CAKing Abdul Aziz University Hospital · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe diagnosis and treatment of indeterminate dominant strictures (DS) in patients with primary sclerosing cholangitis (PSC) is challenging and the literature on the subject is scarce.

objectivesThis review aims to appraise and synthesize the evidence published in the English-language medical literature on this topic.

methodsScientific papers published from 1950 until week 4 of July 2010 were extracted from MEDLINE, Ovid Medline In-Process, the Cochrane Database of Systematic Reviews, the Database of Systematic Reviews, the Database of Abstracts of Reviews of Effects, EMBASE, PubMed and the National Library of Medicine Gateway.

resultsStrategies for the optimal management of DS in PSC patients are supported only by level II and III evidence. Intraductal endoscopic ultrasound appears to be the most sensitive (64%) and specific (95%) diagnostic test for the evaluation of DS in PSC. Endoscopic and percutaneous dilatations achieve 1- and 3-year palliation in 80% and 60% of patients, respectively. Although dilatation and stenting are the most common palliative interventions in DS, no randomized trials on the optimal duration of treatment have been conducted.

conclusionsIn benign DS, endoscopic dilatation with short-term stenting seems to be effective and safe and does not increase the risks for malignant transformation or complications after liver transplantation. Surgical bile duct resection and/or bilioenteric bypass are indicated only in patients with preserved liver function.

Indexed as

Biliary Tract Surgical ProceduresCholangitis, SclerosingCholestasisConstriction, PathologicDiagnostic Techniques, Digestive SystemDilatationEndoscopy, Digestive SystemEndosonographyEvidence-Based MedicineHumansPalliative CarePredictive Value of TestsStentsTreatment Outcome

Identifiers

PMID21241424
PMCPMC3044341
OpenAlexW2041538832

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.