Evidence map›Paper›PMID 21240966›Full record

ArticleArthritis care & research2011

Pneumocystis jiroveci pneumonia in giant cell arteritis: A case series.

Tanaz A Kermani, Steven R Ytterberg, Kenneth J Warrington

Open access · greenAbstract read
In one paragraph

Article in Arthritis care & research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Avicenna journal of medicine · 2023
    Review
  4. Article
  5. Duration of prednisone treatment before development ofJournal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2022
    Article
  6. Article
  7. Review
  8. Morbidity and Mortality of Large-Vessel Vasculitides.Current rheumatology reports · 2020
    Review
  9. Article
  10. Updates in the Diagnosis and Management of Giant Cell Arteritis.Current neurology and neuroscience reports · 2019
    Review
  11. Therapy and Management ofJournal of fungi (Basel, Switzerland) · 2018
    Review
  12. Review
  13. Infection Risk and Safety of Corticosteroid Use.Rheumatic diseases clinics of North America · 2016
    Review
  14. Article
  15. Review
  16. [Large vessel vasculitis].Zeitschrift fur Rheumatologie · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Tanaz A KermaniMayo Clinic, Rochester, Minnesota, USA. kermani.tanaz@mayo.edu
Steven R Ytterberg
Kenneth J Warrington
Mayo Clinic · USWinnMed · US

Funding

VASCULITIS CLINICAL RESEARCH NETWORK (VCRN): RARE DISEASEU54RR019497 · NCRR · BOSTON UNIVERSITY MEDICAL CAMPUS · PI MERKEL, PETER A · 2003 to 2008
$6.1M
NCRR NIH HHS U54 RR019497NCRR NIH HHS U54-RR-019497
6 · The paper itself

Abstract

objectiveTo describe the clinical presentation, laboratory findings, and outcome of patients with Pneumocystis jiroveci pneumonia (PCP) and biopsy-proven giant cell arteritis (GCA) seen at a tertiary referral center.

methodsUsing International Classification of Diseases, Ninth Revision codes, all patients with GCA and PCP between January 1, 1976 and December 31, 2008 were identified. Medical records were reviewed. PCP was defined by the identification of Pneumocystis jiroveci organisms in the clinical setting of pneumonia.

resultsWe identified 7 patients with GCA (5 women and 2 men) who developed PCP (the mean ± SD age at diagnosis was 71.6 ± 6.1 years). The median time from GCA diagnosis to PCP diagnosis was 3 months (range 1-18 months). All patients were taking prednisone (the median dosage 50 mg/day [range 30-80]) when diagnosed as having PCP. No patients were receiving PCP prophylaxis. PCP was diagnosed by positive smear on bronchoalveolar lavage fluid in 6 patients (86%) and by positive sputum polymerase chain reaction in 1 patient. All the patients were hospitalized (median duration 17 days [range 12-39 days]). Four patients (57%) were admitted to the intensive care unit. Three patients (43%) required mechanical ventilation. Two patients (29%) died; both were on mechanical ventilation.

conclusionAlthough PCP is rare among patients with GCA, this preventable infection is associated with significant morbidity and mortality.

Indexed as

AgedAged, 80 and overBiopsyBronchoalveolar Lavage FluidCritical CareFemaleGiant Cell ArteritisGlucocorticoidsHumansLength of StayMaleMinnesotaPneumocystis cariniiPneumonia, PneumocystisPrednisoneRespiration, ArtificialGlucocorticoidsPrednisone

Identifiers

PMID21240966
PMCPMC3091984
OpenAlexW1997836601

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.