Evidence map›Paper›PMID 21240001›Full record

Trial reportJournal of burn care & research : official publication of the American Burn Association

Computer decision support software safely improves glycemic control in the burn intensive care unit: a randomized controlled clinical study.

Elizabeth A Mann, John A Jones, Steven E Wolf, Charles E Wade

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of burn care & research : official publication of the American Burn Association. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 5 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 5 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Article
  7. Observational
  8. Inpatient and Outpatient Technologies to Assist in the Management of Insulin Dosing.Clinical diabetes : a publication of the American Diabetes Association · 2020
    Article
  9. Review
  10. Article
  11. Computerized decision support in adult and pediatric critical care.World journal of critical care medicine · 2013
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Elizabeth A MannUS Army Burn Center, United States Army Institute of Surgical Research, Brooke Army Medical Center, San Antonio, Texas, USA.
John A Jones
Steven E Wolf
Charles E Wade
United States Army · US

Funding

Effects of Insulin on Post-Burn HypermetabolismR01GM063120 · NIGMS · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI WOLF, STEVEN E · 2003 to 2007
$1.4M
NIGMS NIH HHS 1 R01 GM063120-04NIGMS NIH HHS R01 GM063120
6 · The paper itself

Abstract

The optimal method for glycemic control in the critically burned patient is unknown. The purpose of this randomized controlled study was to determine the safety and efficacy of computer decision support software (CDSS) to control serum glucose concentration in a burn intensive care unit. Eighteen adult burn/trauma patients receiving continuous insulin infusion were initially randomized to receive glucose management by a traditional paper protocol or a computer protocol (CP) for 72 hours and then crossed over to the alternate method for an additional 72 hours. Time in target glucose range (range: 80-110 mg/dl) was higher in the CP group (47 ± 17% vs 41 ± 16.6%; P ≤ .05); time over target range was not significantly reduced in the CP group (49 ± 17.8% vs 54 ± 17.1%; P = .08); and no difference was noted in time under target range of 80 mg/dl (CP: 4.5 ± 2.8%, paper protocol: 4.8 ± 3.3%; P = .8), less than 60 mg/dl (P = .7), and less than 40 mg/dl (P = 1.0). Severe hypoglycemic events (<40 mg/dl) did not differ from the CP group compared with historical controls for patients receiving no insulin (P = .6). More glucose measurements were performed in the CP group (P = .0003), and nursing staff compliance with CP recommendations was greater (P < .0001). Glycemic control using CDSS is safe and effective for the critically burned patient. Time in target range improved without increase in hypoglycemic events. CDSS enhanced consistency in practice, providing standardization among nursing staff.

Indexed as

Blood GlucoseSafetyAcute DiseaseAdultBurnsBurn UnitsDecision Support Systems, ClinicalFemaleHumansHyperglycemiaHypoglycemiaIntensive Care UnitsLength of StayMaleMiddle AgedNomogramsBlood Glucose

Identifiers

PMID21240001
PMCPMC3042492
OpenAlexW2032532481

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.