ArticleVirology2011
The structure of avian polyomavirus reveals variably sized capsids, non-conserved inter-capsomere interactions, and a possible location of the minor capsid protein VP4.
Article in Virology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 30 citations in OpenAlex.
- SYK Signalling in NLRP3 Inflammasome-Mediated Response of Murine Microglia Activated by Immune Complexes Formed of Viral Proteins and Specific IgG.European journal of immunology · 2026Article
- Therapeutic potential of flavonols in the treatment of JCPyV.Microbiology spectrum · 2025Article
- Complexities of JC Polyomavirus Receptor-Dependent and -Independent Mechanisms of Infection.Viruses · 2022Review
- Detection of Quebec Polyomavirus DNA in Samples from Different Patient Groups.Microorganisms · 2021Article
- Review
- Article
- The Structure of an Infectious Human Polyomavirus and Its Interactions with Cellular Receptors.Structure (London, England : 1993) · 2018Article
- Agnoprotein Is an Essential Egress Factor during BK Polyomavirus Infection.International journal of molecular sciences · 2018Article
- Role of Condensing Particles in Polymer Confinement: A Model for Virus-Packed "Minichromosomes".Biophysical journal · 2017Article
- Article
- New Structural Insights into the Genome and Minor Capsid Proteins of BK Polyomavirus using Cryo-Electron Microscopy.Structure (London, England : 1993) · 2016Article
- Production of recombinant VP1-derived virus-like particles from novel human polyomaviruses in yeast.BMC biotechnology · 2015Article
- Identification of Two Novel Members of the Tentative Genus Wukipolyomavirus in Wild Rodents.PloS one · 2015Article
- Structural optimization of a retrograde trafficking inhibitor that protects cells from infections by human polyoma- and papillomaviruses.Bioorganic & medicinal chemistry · 2014Article
- The human alpha defensin HD5 neutralizes JC polyomavirus infection by reducing endoplasmic reticulum traffic and stabilizing the viral capsid.Journal of virology · 2014Article
- Conformational shift of a major poliovirus antigen confirmed by immuno-cryogenic electron microscopy.Journal of immunology (Baltimore, Md. : 1950) · 2013Article
- Effect of capsid confinement on the chromatin organization of the SV40 minichromosome.Nucleic acids research · 2013Article
- Cysteine residues in the major capsid protein, Vp1, of the JC virus are important for protein stability and oligomer formation.PloS one · 2013Article
- The VP1 subunit of JC polyomavirus recapitulates early events in viral trafficking and is a novel tool to study polyomavirus entry.Virology · 2012Article
- Structure of the Fab-labeled "breathing" state of native poliovirus.Journal of virology · 2012Article
Corrections and comments
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Authors and funding
13 authors at 5 institutions in 2 countries.
Funding
Abstract
Avian polyomavirus (APV) causes a fatal, multi-organ disease among several bird species. Using cryogenic electron microscopy and other biochemical techniques, we investigated the structure of APV and compared it to that of mammalian polyomaviruses, particularly JC polyomavirus and simian virus 40. The structure of the pentameric major capsid protein (VP1) is mostly conserved; however, APV VP1 has a unique, truncated C-terminus that eliminates an intercapsomere-connecting β-hairpin observed in other polyomaviruses. We postulate that the terminal β-hairpin locks other polyomavirus capsids in a stable conformation and that absence of the hairpin leads to the observed capsid size variation in APV. Plug-like density features were observed at the base of the VP1 pentamers, consistent with the known location of minor capsid proteins VP2 and VP3. However, the plug density is more prominent in APV and may include VP4, a minor capsid protein unique to bird polyomaviruses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.