Evidence map›Paper›PMID 21235770›Full record

SynthesisHealth and quality of life outcomes2011

Heath-related quality of life in Spanish breast cancer patients: a systematic review.

María Concepción Delgado-Sanz, María José García-Mendizábal, Marina Pollán, Maria João Forjaz, Gonzalo López-Abente, Nuria Aragonés, Beatriz Pérez-Gómez

Registry-linked trialAbstract readSystematic Review
In one paragraph

Synthesis in Health and quality of life outcomes, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01990430 (Integrative Exercise and Life Style Intervention Increase Leisure Time Activity in Breast Cancer Patients.), which is not on this map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01990430 naunknown statusnot on this mapstarted 2013, after this paper: background citation

Integrative Exercise and Life Style Intervention Increase Leisure Time Activity in Breast Cancer Patients.

TypeinterventionalSponsorUniversidad Politecnica de MadridRan2013 to 2014Enrolled60ConditionsQuality of LifeArmsExercise Intervention
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Reference values of EORTC QLQ-C30, EORTC QLQ-BR23, and EQ-5D-5L for women with non-metastatic breast cancer at diagnosis and 2 years after.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
    Article
  4. Health-related quality of life among breast cancer patients in India.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  5. Article
  6. Review
  7. Observational
  8. Article
  9. Article
  10. Review
  11. Article
  12. Determinants of satisfaction with life and self-esteem in women with breast cancer.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019
    Article
  13. Article
  14. Article
  15. Comparison of the impact of cancer between British and US long-term non-Hodgkin lymphoma survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2017
    Article
  16. Assessing health-related quality of life in patients with breast cancer: a systematic and standardized comparison of available instruments using the EMPRO tool.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2016
    Article
  17. Review
  18. Article
  19. Patient-centred care: making cancer treatment centres accountable.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2014
    Review
  20. Palliative treatment of colorectal cancer in Germany: cost of care and quality of life.The European journal of health economics : HEPAC : health economics in prevention and care · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

María Concepción Delgado-SanzDepartment of Cancer and Environmental Epidemiology, National Centre for Epidemiology, Carlos III Institute of Health, Avda. Monforte de Lemos 5, Madrid, Spain.
María José García-Mendizábal
Marina Pollán
Maria João Forjaz
Gonzalo López-Abente
Nuria Aragonés
Beatriz Pérez-Gómez

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBreast cancer is one of the oncological diseases in which health-related quality of life (HRQL) has been most studied. This is mainly due to its high incidence and survival. This paper seeks to: review published research into HRQL among women with breast cancer in Spain; analyse the characteristics of these studies; and describe the instruments used and main results reported.

methodsThe databases consulted were MEDLINE, EMBASE, PsycINFO, Dialnet, IBECS, CUIDEN, ISOC and LILACS. The inclusion criteria required studies to: 1) include Spanish patients, and a breakdown of results where other types of tumours and/or women from other countries were also included; and, 2) furnish original data and measure HRQL using a purpose-designed questionnaire. The methodological quality of studies was assessed.

resultsSpain ranked midway in the European Union in terms of the number of studies conducted on the HRQL of breast cancer patients. Of the total of 133 papers published from 1993 to 2009, 25 met the inclusion criteria. Among them, only 12 were considered as having good or excellent quality. A total of 2236 women participated in the studies analysed. In descending order of frequency, the questionnaires used were the EORTC, FACT-B, QL-CA-Afex, SF-12, FLIC, RSCL and CCV. Five papers focused on validation or adaptation of questionnaires. Most papers examined HRQL in terms of type of treatment. Few differences were detected by type of chemotherapy, with the single exception of worse results among younger women treated with radiotherapy. In the short term, better results were reported for all HRQL components by women undergoing conservative rather than radical surgery. Presence of lymphedema was associated with worse HRQL. Three studies assessed differences in HRQL by patients' psychological traits. Psychosocial disorder and level of depression and anxiety, regardless of treatment or disease stage, worsened HRQL. In addition, there was a positive effect among patients who reported having a "fighting spirit" and using "denial" as a defence mechanism. One study found that breast cancer patients scored worse than did healthy women on almost all SF-12 scales.

conclusionResearch into health-related quality of life of breast-cancer patients is a little developed field in Spain.

Indexed as

Breast NeoplasmsQuality of LifeAttitude to HealthFemaleHealth Services ResearchHealth Status IndicatorsHumansPsychometricsSpainSurveys and QuestionnairesValidation Studies as Topic

Identifiers

PMID21235770
PMCPMC3031190

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.