ArticleVirology journal2011
Hepatitis C virus genotypes circulating in district Swat of Khyber Pakhtoonkhaw, Pakistan.
Article in Virology journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Hepatitis C virus prevalence and genotype distribution in Pakistan: Comprehensive review of recent data.World journal of gastroenterology · 2016Pooled it
- Hepatitis C virus genotypes in Pakistan: a systemic review.Virology journal · 2011Pooled it
- Occurrence of genetic modifications in core, 5'UTR and NS5b of HCV associated with viral response to treatment.Virology journal · 2014Trial
- Hepatitis C Virus Infection and Intrinsic Disorder in the Signaling Pathways Induced by Toll-Like Receptors.Biology · 2022Review
- Detection, quantification and genotype distribution of HCV patients in Lahore, Pakistan by real-time PCR.African health sciences · 2020Article
- Molecular characterization and clinical epidemiology of HCV in District Dir (Lower), Pakistan.Virusdisease · 2018Article
- A case of a patient infected with a hepatitis C virus genotype 3a multidrug resistant variant in Pakistan.Infectious diseases of poverty · 2018Article
- Prevalence of hepatitis-C virus genotypes and potential transmission risks in Malakand Khyber Pakhtunkhwa, Pakistan.Virology journal · 2017Article
- Prevalence of Hepatitis C Virus Genotypes Among Patients in Countries of the Eastern Mediterranean Regional Office of WHO (EMRO): A Systematic Review and Meta-Analysis.Hepatitis monthly · 2016Review
- Article
- Phylogenetic analysis of HCV subgenotypes in patients from Sichuan province in China based on the NS5B region.International journal of molecular medicine · 2015Article
- Distribution and predominance of genotype 3 in hepatitis C virus carriers in the province of kahramanmaras, Turkey.Hepatitis monthly · 2015Article
- Diagnostically untypable hepatitis C virus variants: it is time to resolve the problem.World journal of gastroenterology · 2014Article
- Increased prevalence of hepatitis C virus subtype 6a in China: a comparison between 2004-2007 and 2008-2011.Archives of virology · 2014Article
- Emergence of genetically variant Hepatitis C virus population in response to increased antiviral drug pressure, Pakistan.Virus genes · 2014Article
- Inhibitory effect of kaolin minerals compound against hepatitis C virus in Huh-7 cell lines.BMC research notes · 2014Article
- Prevalence of hepatitis C virus genotypes in district bannu, khyber pakhtunkhwa, pakistan.Hepatitis research and treatment · 2014Article
- Prevalence of active hepatitis C virus infections among general public of Lahore, Pakistan.Virology journal · 2013Article
- Prevalence of HCV genotypes in district Mardan.Virology journal · 2013Article
- Determination of HCV genotypes and viral loads in chronic HCV infected patients of Hazara Pakistan.Virology journal · 2011Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hepatitis C virus (HCV) is the leading cause of chronic hepatitis worldwide and its subtypes/genotypes are clinically important for clinical management and vaccine development. The present study describes frequency distribution of different HCV genotypes and their treatment status in HCV RNA positive patients from district Swat. A total of 185 HCV infected sera were analyzed by molecular genotyping assay. The most prevalent genotype was 3a (34.1%), followed by 2a (8.1%), 3b (7%) and 1a (5.4%). The samples found untypable by the present method of genotypes was 37.8% while, patients with mixed genotype infections were 7.6%. More than 80% of untypable cases were from those HCV patients who had received interferon plus ribavirin standard therapy in the past and either were non-responders and were relapsed thereafter or were under treatment. In conclusion, genotype 3a is the most prevalent HCV genotype in the region. A high prevalence rate of untypable genotypes is present in treated patients that need further investigation for the successful genotyping by developing new assays or using viral sequencing method.
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