ArticleCellular and molecular neurobiology2011
No observable relationship between the 12 genes of nervous system and reasoning skill in a young Chinese Han population.
Article in Cellular and molecular neurobiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- REST Is Not Resting: REST/NRSF in Health and Disease.Biomolecules · 2023Review
- The potential role of dopamine D₃ receptor neurotransmission in cognition.European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology · 2013Review
- Rationality and emotionality: serotonin transporter genotype influences reasoning bias.Social cognitive and affective neuroscience · 2013Article
- An association study on the polymorphisms of dopaminergic genes with working memory in a healthy Chinese Han population.Cellular and molecular neurobiology · 2012Article
- An association study of the genetic polymorphisms in 13 neural plasticity-related genes with semantic and episodic memories.Journal of molecular neuroscience : MN · 2012Article
Corrections and comments
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Authors and funding
9 authors.
Funding
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Abstract
Reasoning skill is an advanced cognitive ability which is needed for drawing inferences from given information. It is well known that the ability depends on the neural network of the frontal and parietal brain regions. In this study, we hypothesized that some genes involved in neurotransmitter systems were related to reasoning skill. To confirm this hypothesis, we examined the effects of 13 genes (BDNF, NRSF, COMT, DBH, DRD(2), DRD(3), DAT(1), MAOA, GRM(1), GRIN2B, TPH(2), 5-HT(2A), and 5-HT(6)) in neurotransmitter systems on the non-verbal reasoning and verbal reasoning skills. The results indicated there were on significant effects of the 17 functional variants of these genes on the performance of non-verbal reasoning and verbal analogical reasoning skills (χ(2) > 3.84, df = 1, P > 0.05). This study suggests that some of the functional variations in BDNF, COMT, DBH, DRD(2), DRD(3), MAOA, 5-HT(2A), 5-HT(6), GRM(1), and GRIN2B have no observable effects on the certain reasoning skills in a young healthy Chinese Han population.
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