Evidence map›Paper›PMID 21234776›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2011

Medulloblastoma and gliomatosis cerebri: rare brain tumors in multiple sclerosis patients.

Ana Alexandra Duarte Martins da Silva, Sara Marta Pereira dos Santos Cavaco, Ricardo Jorge Ferreira Taipa, Pedro Ricardo Soares Pinto, Manuel Jorge Rocha Melo Pires

Abstract readCase Reports
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In one paragraph

Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ana Alexandra Duarte Martins da SilvaServiço de Neurologia, Largo do Prof Abel Salazar, Centro Hospitalar do Porto/Hospital de Santo António, 4099-001 Porto, Portugal. anadmsilva@yahoo.com
Sara Marta Pereira dos Santos Cavaco
Ricardo Jorge Ferreira Taipa
Pedro Ricardo Soares Pinto
Manuel Jorge Rocha Melo Pires

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The simultaneous appearance of both multiple sclerosis (MS) and central nervous system (CNS) tumors is relatively uncommon. Whether the co-existence of two diseases is due to chance alone or the result of a causal relationship is still a matter of debate. There is also controversy about the effect of long-term exposure of MS patients to immunomodulatory drugs on the incidence of cancer. This paper reports two cases of rare CNS tumors (i.e., medulloblastoma and gliomatosis cerebri) in adult MS patients. Our cases emphasize that when uncommon neurological features appear in patients with MS, brain magnetic resonance imaging (MRI) ought to be done and brain biopsy should be considered to exclude a concomitant CNS disorder. These procedures are essential for the differential diagnosis and early treatment.

Indexed as

AdultBrain NeoplasmsCerebellar NeoplasmsFemaleHumansMaleMedulloblastomaMiddle AgedMultiple SclerosisNeoplasms, Neuroepithelial

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.