ArticleClinical oral investigations2012
Antibacterial properties and human gingival fibroblast cell compatibility of TiO2/Ag compound coatings and ZnO films on titanium-based material.
Article in Clinical oral investigations, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 54 citations in OpenAlex.
- In Vitro Study of Zirconia Surface Modification for Dental Implants by Atomic Layer Deposition.International journal of molecular sciences · 2023Article
- Current Research on Zinc Oxide Nanoparticles: Synthesis, Characterization, and Biomedical Applications.Nanomaterials (Basel, Switzerland) · 2022Review
- Mechanical and Wetting Properties of TaMaterials (Basel, Switzerland) · 2022Article
- Efficient isolation of human gingival stem cells in a new serum-free medium supplemented with platelet lysate and growth hormone for osteogenic differentiation enhancement.Stem cell research & therapy · 2022Article
- NanoZnO-modified titanium implants for enhanced anti-bacterial activity, osteogenesis and corrosion resistance.Journal of nanobiotechnology · 2021Review
- Thin Films Deposition of TaMaterials (Basel, Switzerland) · 2021Article
- An overview of recent progress in dental applications of zinc oxide nanoparticles.RSC advances · 2021Review
- Article
- The role of macrophage polarization on fibroblast behavior-an in vitro investigation on titanium surfaces.Clinical oral investigations · 2018Article
- Synergistic mechanism of AgJournal of nanobiotechnology · 2018Article
- Biocompatibility of Titania Nanotube Coatings Enriched with Silver Nanograins by Chemical Vapor Deposition.Nanomaterials (Basel, Switzerland) · 2017Article
- Evaluation of Antibacterial Effects of Silver-Coated Stainless Steel Orthodontic Brackets.Journal of dentistry (Tehran, Iran) · 2016Article
- Antibacterial Activity of As-Annealed TiO2 Nanotubes Doped with Ag Nanoparticles against Periodontal Pathogens.Bioinorganic chemistry and applications · 2014Article
- Analyses of antibacterial activity and cell compatibility of titanium coated with a Zr-C-N film.PloS one · 2013Article
- Antibacterial effect of silver-platinum coating for orthodontic appliances.The Angle orthodontist · 2012Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Titanium (Ti)-based materials are widely used in biomedical implant components and are applied successfully in various types of bone-anchored reconstructions. However, in dental implants the Ti materials contact not only bone but also gingival tissues, and are partially exposed to the oral cavity that includes bacteria. This study used titania and silver (TiO(2)/Ag) compound coatings and zinc oxide (ZnO) films to enhance the antibacterial activity of the Ti-based implant. The hydrophobicity of each sample was examined by measuring the contact angle. Streptococcus mutans and human gingival fibroblast (HGF) was cultured on the coated samples, and the antibacterial effects and cell compatibility were determined using a Syto9 fluorescence staining and MTT methods. For the TiO(2)/Ag samples, depositing Ag on the plate at a higher power (which increased the proportion of Ag) increased the contact angle and the hydrophobicity. The bacterial count was lowest for the 50 W TiO(2)/Ag sample, which contained 5.9% Ag. The contact angles of the ZnO samples did not show the same tendency. The antibacterial effect was higher on ZnO-coated samples since bacterial count was threefold lower on ZnO samples as compared to control samples (Ti plate). From the MTT assay test, the mean optical density values for TiO(2)/Ag-coated samples after 72 h of HGF adhesion were similar to the value obtained from the uncoated Ti. However, biocompatibility was lower on ZnO films than in control samples. Conclusively, the antibacterial activity was higher but the cell compatibility was lower on ZnO films than on TiO(2)/Ag coatings.
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