Evidence map›Paper›PMID 21234096›Full record

ArticleJournal of skin cancer2011

Deciphering squamous cell carcinoma using multidimensional genomic approaches.

Ewan A Gibb, Katey S S Enfield, Ivy F L Tsui, Raj Chari, Stephen Lam, Carlos E Alvarez, Wan L Lam

Abstract read
In one paragraph

Article in Journal of skin cancer, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ewan A GibbDepartment of Integrative Oncology, British Columbia Cancer Agency Research Centre, Vancouver BC, Canada V5Z 1L3.
Katey S S Enfield
Ivy F L Tsui
Raj Chari
Stephen Lam
Carlos E Alvarez
Wan L Lam

Funding

Novel Reagents and New Biomarkers for Lung CancerU01CA084971 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI GAZDAR, ADI F. · 1999 to 2009
$4.5M
DNA Copy Number Variation in DogsR21HG004663 · NHGRI · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI ALVAREZ, CARLOS E. · 2009 to 2010
$396k
NCI NIH HHS U01 CA084971NHGRI NIH HHS R21 HG004663
6 · The paper itself

Abstract

Squamous cell carcinomas (SqCCs) arise in a wide range of tissues including skin, lung, and oral mucosa. Although all SqCCs are epithelial in origin and share common nomenclature, these cancers differ greatly with respect to incidence, prognosis, and treatment. Current knowledge of genetic similarities and differences between SqCCs is insufficient to describe the biology of these cancers, which arise from diverse tissue origins. In this paper we provide a general overview of whole genome approaches for gene and pathway discovery and highlight the advancement of integrative genomics as a state-of-the-art technology in the study of SqCC genetics.

Identifiers

PMID21234096
PMCPMC3017908

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.