Evidence map›Paper›PMID 21233509›Full record

ReviewClinical microbiology reviews2011

Zoonotic potential and molecular epidemiology of Giardia species and giardiasis.

Yaoyu Feng, Lihua Xiao

Open access · greenAbstract readReview
In one paragraph

Review in Clinical microbiology reviews, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 575 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
575citing papers in PubMed, 8 pooled it
31.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

575 citing papers in PubMed, 8 syntheses or guidelines pooled it, 1,137 citations in OpenAlex.

  1. Pooled it
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  7. Guideline
  8. Pooled it
  9. Article
  10. Article
  11. Food and waterborne parasitology · 2026
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  12. Article
  13. Molecular characterization and zoonotic potential ofFood and waterborne parasitology · 2026
    Article
  14. Article
  15. Regarding the Zoonotic Transmission ofAnimals : an open access journal from MDPI · 2026
    Review
  16. Article
  17. Prevalence and molecular characterisation ofInternational journal for parasitology. Parasites and wildlife · 2026
    Article
  18. Article
  19. Molecular epidemiology and genotype diversity of Dientamoeba fragilis in a Czech hospital-based cohort: higher prevalence in paediatric patients and evidence of mixed G1/G2 infection in a single patient.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  20. Analysis ofInfection and immunity · 2026
    Article

515 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Yaoyu FengState Key Laboratory of Bioreactor Engineering, School of Resource and Environmental Engineering, East China University of Science and Technology, Shanghai, China. yyfeng@ecust.edu.cn
Lihua Xiao
Centers for Disease Control and Prevention · USEast China University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Molecular diagnostic tools have been used recently in assessing the taxonomy, zoonotic potential, and transmission of Giardia species and giardiasis in humans and animals. The results of these studies have firmly established giardiasis as a zoonotic disease, although host adaptation at the genotype and subtype levels has reduced the likelihood of zoonotic transmission. These studies have also identified variations in the distribution of Giardia duodenalis genotypes among geographic areas and between domestic and wild ruminants and differences in clinical manifestations and outbreak potentials of assemblages A and B. Nevertheless, our efforts in characterizing the molecular epidemiology of giardiasis and the roles of various animals in the transmission of human giardiasis are compromised by the lack of case-control and longitudinal cohort studies and the sampling and testing of humans and animals living in the same community, the frequent occurrence of infections with mixed genotypes and subtypes, and the apparent heterozygosity at some genetic loci for some G. duodenalis genotypes. With the increased usage of multilocus genotyping tools, the development of next-generation subtyping tools, the integration of molecular analysis in epidemiological studies, and an improved understanding of the population genetics of G. duodenalis in humans and animals, we should soon have a better appreciation of the molecular epidemiology of giardiasis, the disease burden of zoonotic transmission, the taxonomy status and virulences of various G. duodenalis genotypes, and the ecology of environmental contamination.

Indexed as

AnimalsGenotypeGiardiaGiardiasisHumansMolecular EpidemiologyMolecular TypingParasitologyZoonoses

Identifiers

PMID21233509
PMCPMC3021202
OpenAlexW2147043577

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.