Evidence map›Paper›PMID 21233233›Full record

ReviewAJNR. American journal of neuroradiology2011

Endovascular stroke treatment today.

I Q Grunwald, A K Wakhloo, S Walter, A J Molyneux, J V Byrne, S Nagel, A L Kühn, M Papadakis, K Fassbender, J S Balami and 3 more

Open access · hybridAbstract readReview
In one paragraph

Review in AJNR. American journal of neuroradiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Therapeutic management of ischemic stroke.Naunyn-Schmiedeberg's archives of pharmacology · 2024
    Review
  3. Article
  4. Review
  5. Article
  6. Endovascular therapy for ischemic stroke.Journal of clinical neurology (Seoul, Korea) · 2015
    Review
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

I Q GrunwaldBiomedical Research Centre, University of Oxford, UK. i.grunwald@web.de
A K Wakhloo
S Walter
A J Molyneux
J V Byrne
S Nagel
A L Kühn
M Papadakis
K Fassbender
J S Balami
M Roffi
H Sievert
A Buchan
University of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was to review current treatment options in acute ischemic stroke, focusing on the latest advances in the field of mechanical recanalization. These devices recently made available for endovascular intracranial thrombectomy show great potential in acute stroke treatments. Compelling evidence of their recanalization efficacy comes from current mechanical embolectomy trials. In addition to allowing an extension of the therapeutic time window, mechanical recanalization devices can be used without adjuvant thrombolytic therapy, thus diminishing the intracranial bleeding risk. Therefore, these devices are particularly suitable in patients in whom thrombolytic therapy is contraindicated. IV and IA thrombolysis and bridging therapy are viable options in acute stroke treatment. Mechanical recanalization devices can potentially have a clinically relevant impact in the interventional treatment of stroke, but at the present time, a randomized study would be beneficial.

Indexed as

ThrombectomyThrombolytic TherapyAcute DiseaseBrain IschemiaHumansStroke

Identifiers

PMID21233233
PMCPMC7965694
OpenAlexW2140390429

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.