Trial reportOsteoarthritis and cartilage2011
A randomized trial of patellofemoral bracing for treatment of patellofemoral osteoarthritis.
Trial report in Osteoarthritis and cartilage, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 27 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Bracing in Patellofemoral Osteoarthritis: A Clinical Trial
Bracing for Patellofemoral Osteoarthritis. A Prospective Randomized Study of the Treatment of Patellofemoral Arthritis by an Orthosis
Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 71 citations in OpenAlex.
- Adjunctive therapies in addition to land-based exercise therapy for osteoarthritis of the hip or knee.The Cochrane database of systematic reviews · 2022Pooled it
- Management of patellofemoral joint osteoarthritis using biomechanical device therapy: a systematic review with meta-analysis.Systematic reviews · 2021Pooled it
- A systematic review of randomised controlled trials assessing effectiveness of prosthetic and orthotic interventions.PloS one · 2018Pooled it
- With a biomechanical treatment in knee osteoarthritis, less knee pain did not correlate with synovitis reduction.BMC musculoskeletal disorders · 2017Trial
- A randomised trial of a brace for patellofemoral osteoarthritis targeting knee pain and bone marrow lesions.Annals of the rheumatic diseases · 2015Trial
- Lateral wedge insoles for medial knee osteoarthritis: 12 month randomised controlled trial.BMJ (Clinical research ed.) · 2011Trial
- Early Patellofemoral Osteoarthritis Following ACL Reconstruction: A Narrative Review.Healthcare (Basel, Switzerland) · 2026Review
- Autologous protein solution as selective treatment for advanced patellofemoral osteoarthritis in the middle-aged female patient: 54% response rate at 1 year follow-up.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2021Article
- Preliminary Evaluation of a New Orthotic for Patellofemoral and Multicompartment Knee Osteoarthritis.Rehabilitation research and practice · 2021Article
- Biomechanical Study of a Tricompartmental Unloader Brace for Patellofemoral or Multicompartment Knee Osteoarthritis.Frontiers in bioengineering and biotechnology · 2020Article
- Tibial tuberosity to trochlear groove distance and its association with patellofemoral osteoarthritis-related structural damage worsening: data from the osteoarthritis initiative.European radiology · 2018Article
- A 6-week hip muscle strengthening and lumbopelvic-hip core stabilization program to improve pain, function, and quality of life in persons with patellofemoral osteoarthritis: a feasibility pilot study.Pilot and feasibility studies · 2018Article
- Clinical Significance of Medial Versus Lateral Compartment Patellofemoral Osteoarthritis: Cross-Sectional Analyses in an Adult Population With Knee Pain.Arthritis care & research · 2017Observational
- Is the effectiveness of patellofemoral bracing modified by patellofemoral alignment and trochlear morphology?BMC musculoskeletal disorders · 2017Article
- Changes in patellofemoral and tibiofemoral joint cartilage damage and bone marrow lesions over 7 years: the Multicenter Osteoarthritis Study.Osteoarthritis and cartilage · 2016Article
- 2016 Patellofemoral pain consensus statement from the 4th International Patellofemoral Pain Research Retreat, Manchester. Part 1: Terminology, definitions, clinical examination, natural history, patellofemoral osteoarthritis and patient-reported outcome measures.British journal of sports medicine · 2016Article
- The relation of MRI-detected structural damage in the medial and lateral patellofemoral joint to knee pain: the Multicenter and Framingham Osteoarthritis Studies.Osteoarthritis and cartilage · 2015Article
- The diagnostic performance of anterior knee pain and activity-related pain in identifying knees with structural damage in the patellofemoral joint: the Multicenter Osteoarthritis Study.The Journal of rheumatology · 2014Article
- Patellofemoral pain: an update on diagnostic and treatment options.Current reviews in musculoskeletal medicine · 2013Article
- The relationship between patellofemoral and tibiofemoral morphology and gait biomechanics following arthroscopic partial medial meniscectomy.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
Abstract
purposeThe number of effective knee osteoarthritis (OA) interventions, especially those tailored to specific compartmental involvement, are small. The objective of this study was to determine the efficacy of a realigning patellofemoral (PF) brace in improving pain and function among persons with symptomatic lateral PF OA.
methodWe conducted a double blind, randomized crossover trial of a realigning PF brace for persons with lateral PF OA. Participants had lateral PF OA with anterior knee symptoms on most days of the month, lateral PF joint space narrowing, and radiographic evidence of a definite osteophyte in the PF joint. We compared two treatments: (1) Control treatment consisting of a BioSkin Q Brace with patellar realigning strap removed; and (2) Active treatment consisting of a realigning BioSkin Q Brace with the strap applied. For each participant, the trial lasted 18 weeks, including 6 weeks each of active and control treatment period separated by a 6-week washout period. The order of treatments was randomized. The primary outcome was change in knee pain on the visual analog scale (VAS). Secondary outcomes included WOMAC pain, function, and stiffness. An unstructured correlation matrix for observations within participants was used in generalized estimating equation fitting to derive a linear regression model that expressed the relation between the intervention and change in VAS pain.
results80 participants (63 F) with a mean age and body mass index of 61 years and 28 kg/m(2), respectively, were randomized by order of treatment. A model examining the main effects for change in VAS knee pain (0-100) demonstrated no significant treatment effect (-0.68 VAS units, 95% CI: -6.2, 4.8 units, P=0.81) and no differential carryover effect. There was also no significant difference between active and control treatments for WOMAC pain, function, or stiffness outcomes.
conclusionThe effects of a specific realigning PF brace are not of clinical or statistical significance.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.