ArticleJournal of occupational medicine and toxicology (London, England)2011
Is dental amalgam safe for humans? The opinion of the scientific committee of the European Commission.
Article in Journal of occupational medicine and toxicology (London, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed, 112 citations in OpenAlex.
- A Brazilian Minamata disease? Neurologists must be aware of mercury exposure and intoxication.Arquivos de neuro-psiquiatria · 2025Review
- Oxidative genomic damage in pediatric patients exposed to mercury released by dental amalgam.BMC oral health · 2025Article
- Oral State and Salivary Cortisol in Multiple Sclerosis Patients.Biomedicines · 2024Article
- Association between dental amalgam restoration and urine mercury concentrations among young women: a cross-sectional study.Journal of Yeungnam medical science · 2023Article
- Exposure to heavy metals and hormone levels in midlife women: The Study of Women's Health Across the Nation (SWAN).Environmental pollution (Barking, Essex : 1987) · 2023Article
- Decreased trends of using dental amalgam filling for decayed teeth in Taiwan from 1997 to 2013.Journal of dental sciences · 2023Article
- Manganese Intoxication Presenting with Depressive Symptoms: A Case Report.Noro psikiyatri arsivi · 2023Article
- Shared Lifestyle-Related Risk Factors of Cardiovascular Disease and Cancer: Evidence for Joint Prevention.TheScientificWorldJournal · 2023Review
- Article
- Monomer Release from Dental Resins: The Current Status on Study Setup, Detection and Quantification for In Vitro Testing.Polymers · 2022Review
- Urinary Heavy Metals and Longitudinal Changes in Blood Pressure in Midlife Women: The Study of Women's Health Across the Nation.Hypertension (Dallas, Tex. : 1979) · 2021Article
- Gold Compounds and the Anticancer Immune Response.Frontiers in pharmacology · 2021Review
- Validation of a Simple HPLC-UV Method for the Determination of Monomers Released from Dental Resin Composites in Artificial Saliva.Methods and protocols · 2020Article
- Association between Dental Amalgam Filling and Essential Tremor: A Nationwide Population-Based Case Control Study in Taiwan.International journal of environmental research and public health · 2020Article
- Elevated Systemic L-Kynurenine/L-Tryptophan Ratio and Increased IL-1 Beta and Chemokine (CX3CL1, MCP-1) Proinflammatory Mediators in Patients with Long-Term Titanium Dental Implants.Journal of clinical medicine · 2019Article
- Rethinking the Dental Amalgam Dilemma: An Integrated Toxicological Approach.International journal of environmental research and public health · 2019Review
- Increased Systemic Malondialdehyde Levels and Decreased Mo/Co, Co/FeJournal of clinical medicine · 2019Article
- Mercury vapor volatilization from particulate generated from dental amalgam removal with a high-speed dental drill - a significant source of exposure.Journal of occupational medicine and toxicology (London, England) · 2019Article
- Altered urinary porphyrins and mercury exposure as biomarkers for autism severity in Egyptian children with autism spectrum disorder.Metabolic brain disease · 2016Observational
- Class II composite resin restorations: faster, easier, predictable.British dental journal · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It was claimed by the Scientific Committee on Emerging and Newly Identified Health Risks (SCENIHR)) in a report to the EU-Commission that "....no risks of adverse systemic effects exist and the current use of dental amalgam does not pose a risk of systemic disease..." [1, available from: http://ec.europa.eu/health/ph_risk/committees/04_scenihr/docs/scenihr_o_016.pdf].SCENIHR disregarded the toxicology of mercury and did not include most important scientific studies in their review. But the real scientific data show that:(a) Dental amalgam is by far the main source of human total mercury body burden. This is proven by autopsy studies which found 2-12 times more mercury in body tissues of individuals with dental amalgam. Autopsy studies are the most valuable and most important studies for examining the amalgam-caused mercury body burden.(b) These autopsy studies have shown consistently that many individuals with amalgam have toxic levels of mercury in their brains or kidneys.(c) There is no correlation between mercury levels in blood or urine, and the levels in body tissues or the severity of clinical symptoms. SCENIHR only relied on levels in urine or blood.(d) The half-life of mercury in the brain can last from several years to decades, thus mercury accumulates over time of amalgam exposure in body tissues to toxic levels. However, SCENIHR state that the half-life of mercury in the body is only "20-90 days".(e) Mercury vapor is about ten times more toxic than lead on human neurons and with synergistic toxicity to other metals.(f) Most studies cited by SCENIHR which conclude that amalgam fillings are safe have severe methodical flaws.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.