ArticlePhysical review. E, Statistical, nonlinear, and soft matter physics2010
Mean square displacement analysis of single-particle trajectories with localization error: Brownian motion in an isotropic medium.
Article in Physical review. E, Statistical, nonlinear, and soft matter physics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 249 papers.
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Who cites it
249 citing papers in PubMed.
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- Cellular Distribution and Motion of Essential Magnetosome Proteins Expressed in Mammalian Cells.Biosensors · 2025Article
- Nanoscale architecture and dynamics of CaJournal of molecular and cellular cardiology plus · 2025Article
- Graphene-Based Liquid Cell Designs for In Situ Liquid-Phase Transmission Electron Microscopy: Recent Developments and Perspectives.Small science · 2025Review
- Boosting microparticle tracking with neuromorphic cameras by optical modulation.Scientific reports · 2025Article
189 more citing papers are in PubMed but not listed here.
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Authors and funding
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Funding
Abstract
We examine the capability of mean square displacement (MSD) analysis to extract reliable values of the diffusion coefficient D of a single particle undergoing Brownian motion in an isotropic medium in the presence of localization uncertainty. The theoretical results, supported by simulations, show that a simple unweighted least-squares fit of the MSD curve can provide the best estimate of D provided an optimal number of MSD points are used for the fit. We discuss the practical implications of these results for data analysis in single-particle tracking experiments.
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