ArticleThe ISME journal2011
Sequence variability of the pattern recognition receptor Mermaid mediates specificity of marine nematode symbioses.
Article in The ISME journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 37 citations in OpenAlex.
- Differential regulation of degradation and immune pathways underlies adaptation of the ectosymbiotic nematode Laxus oneistus to oxic-anoxic interfaces.Scientific reports · 2022Article
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- Morphology of obligate ectosymbionts revealsZoologica scripta · 2020Article
- Receptors Mediating Host-Microbiota Communication in the Metaorganism: The Invertebrate Perspective.Frontiers in immunology · 2020Review
- Chemosynthetic ectosymbionts associated with a shallow-water marine nematode.Scientific reports · 2019Article
- A Nematode of the Mid-Atlantic Ridge Hydrothermal Vents Harbors a Possible Symbiotic Relationship.Frontiers in microbiology · 2018Article
- Transcriptomic and proteomic insights into innate immunity and adaptations to a symbiotic lifestyle in the gutless marine worm Olavius algarvensis.BMC genomics · 2016Article
- All the microbiology nematodes can teach us.FEMS microbiology ecology · 2016Article
- Transcriptome analyses to investigate symbiotic relationships between marine protists.Frontiers in microbiology · 2015Article
- Shaping the microenvironment: evidence for the influence of a host galaxin on symbiont acquisition and maintenance in the squid-Vibrio symbiosis.Environmental microbiology · 2014Article
- Phylogenetic confirmation of the genusSystematics and biodiversity · 2014Article
- Size-independent symmetric division in extraordinarily long cells.Nature communications · 2014Article
- An ortholog of the Leptospira interrogans lipoprotein LipL32 aids in the colonization of Pseudoalteromonas tunicata to host surfaces.Frontiers in microbiology · 2014Article
- Microsporidia-nematode associations in methane seeps reveal basal fungal parasitism in the deep sea.Frontiers in microbiology · 2014Article
- Nematode-bacterium symbioses--cooperation and conflict revealed in the "omics" age.The Biological bulletin · 2012Review
- Genetic connectivity between north and south Mid-Atlantic Ridge chemosynthetic bivalves and their symbionts.PloS one · 2012Article
- Repeatedly evolved host-specific ectosymbioses between sulfur-oxidizing bacteria and amphipods living in a cave ecosystem.PloS one · 2012Article
- Calling the roll on Laxus oneistus immune defense molecules.Symbiosis (Philadelphia, Pa.) · 2011Article
- Characterization of innate immunity genes in the parasitic nematodeSymbiosis (Philadelphia, Pa.)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Selection of a specific microbial partner by the host is an all-important process. It guarantees the persistence of highly specific symbioses throughout host generations. The cuticle of the marine nematode Laxus oneistus is covered by a single phylotype of sulfur-oxidizing bacteria. They are embedded in a layer of host-secreted mucus containing the mannose-binding protein Mermaid. This Ca(2+)-dependent lectin mediates symbiont aggregation and attachment to the nematode. Here, we show that Stilbonema majum-a symbiotic nematode co-occurring with L. oneistus in shallow water sediment-is covered by bacteria phylogenetically distinct to those covering L. oneistus. Mermaid cDNA analysis revealed extensive protein sequence variability in both the nematode species. We expressed three recombinant Mermaid isoforms, which based on the structural predictions display the most different carbohydrate recognition domains (CRDs). We show that the three CRDs (DNT, DDA and GDA types) possess different affinities for L. oneistus and S. majum symbionts. In particular, the GDA type, exclusively expressed by S. majum, displays highest agglutination activity towards its symbionts and lowest towards its L. oneistus symbionts. Moreover, incubation of L. oneistus in the GDA type does not result in complete symbiont detachment, whereas incubation in the other types does. This indicates that the presence of particular Mermaid isoforms on the nematode surface has a role in the attachment of specific symbionts. This is the first report of the functional role of sequence variability in a microbe-associated molecular patterns receptor in a beneficial association.
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