Evidence map›Paper›PMID 21228852›Full record

ArticleNature2011

Bring on the biomarkers.

George Poste

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Nature, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05338060 (A Systems Approach to Immunotherapy Biomarker Identification Within the Postoperative Wound-Healing Microenvironment in Patients With Gastroesophageal Cancer), which is not on this map. Cited by 238 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
238citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05338060 completednot on this mapstarted 2022, after this paper: background citation

A Systems Approach to Immunotherapy Biomarker Identification Within the Postoperative Wound-Healing Microenvironment in Patients With Gastroesophageal Cancer

TypeobservationalSponsorInova Health Care ServicesRan2022 to 2025Enrolled10ConditionsGastroEsophageal CancerArmsprospective collection of surgical exudates (SEs)
3 · Its place in the literature

Who cites it

238 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Guideline
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Immunosignature system for diagnosis of cancer.Proceedings of the National Academy of Sciences of the United States of America · 2014
    Trial
  9. Review
  10. Article
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  19. Article
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178 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

George PosteComplex Adaptive Systems Initiative, Arizona State University, Scottsdale, Arizona 85257, USA. george.poste@asu.edu

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Biological Specimen BanksBiomarkersBiomedical ResearchCell LineFemaleGene Expression ProfilingGenetics, MedicalHealth Care CostsHumansMaleOligonucleotide Array Sequence AnalysisPharmacogeneticsPrecision MedicineProteomicsReproducibility of ResultsSample SizeBiomarkers

Identifiers

PMID21228852

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.