Evidence map›Paper›PMID 21228825›Full record

ArticleJournal of human hypertension2011

Masked hypertension in young patients after successful aortic coarctation repair: impact on left ventricular geometry and function.

G Di Salvo, B Castaldi, L Baldini, S Gala, F del Gaizo, A D'Andrea, G Limongelli, A F D'Aiello, G Scognamiglio, B Sarubbi and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of human hypertension, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 66 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Article
  4. Hypertension in aortic coarctation.Frontiers in cardiovascular medicine · 2025
    Review
  5. Sleep disordered breathing and adult congenital heart disease.International journal of cardiology. Congenital heart disease · 2024
    Review
  6. Review
  7. Pediatric Hypertension: A Condition That Matters.Children (Basel, Switzerland) · 2024
    Review
  8. Review
  9. Coronary artery disease in adults with congenital heart disease.International journal of cardiology. Congenital heart disease · 2023
    Review
  10. Systemic hypertension in adults with congenital heart diseases.International journal of cardiology. Congenital heart disease · 2023
    Review
  11. Review
  12. Article
  13. Article
  14. Practical application of ABPM in the pediatric nephrology clinic.Pediatric nephrology (Berlin, Germany) · 2020
    Review
  15. Child Blood Pressure Profile in Bali, Indonesia.Open access Macedonian journal of medical sciences · 2019
    Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

G Di SalvoSecond University of Naples, Monaldi Hospital, Chair of Cardiology, Pediatric Cardiology, GUCH Unit, Naples, Italy. giodisal@yahoo.it
B Castaldi
L Baldini
S Gala
F del Gaizo
A D'Andrea
G Limongelli
A F D'Aiello
G Scognamiglio
B Sarubbi
G Pacileo
M G Russo
R Calabrò
Ospedale Monaldi · ITUniversity of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Life expectancy is still reduced in aortic coarctation (AoC) patients despite a successful repair because of late arterial hypertension and atherosclerosis. Masked hypertension (MH) consists of an elevated daytime or awake ambulatory blood pressure (BP) in the presence of a normal BP on conventional measurement at the office. To assess the prevalence of MH among AoC normotensive young patients successfully treated and to evaluate the impact of MH on left ventricular (LV) geometry and function.We studied 76 AoC patients (mean age 14.5±5.7 years, male 64%). According to 24 h ambulatory BP monitoring (ABPM) our sample was divided in real normotensive patients (Group RN, n=40) and MH patients (Group MH, n=36). There was an increased pressure gradient in the aortic arch (15 mm Hg±4 vs 13 mm Hg±4.7, P<0.05), increased LV mass (51 g m(-2.7)±13 vs 46 g m(-2.7)±12, P<0.05), in MH AoC patients. Regional longitudinal deformation properties of the basal septal segment (-15%±2.4 vs -20%±5, P<0.01) and LV twist values (14°±1.6 vs 12°±1.9, P<0.0001) were reduced in the MH group. There is a high prevalence of MH in young patients with repaired AoC, which is associated with abnormal LV structure and function. Clinicians should consider 24 h ABPM measurements in apparently normotensive patients followed up for AoC repair.

Indexed as

Cardiovascular Surgical ProceduresAdolescentAortic CoarctationBlood PressureBlood Pressure Monitoring, AmbulatoryChildEchocardiographyFemaleFollow-Up StudiesHeart VentriclesHumansMaleMasked HypertensionPrevalenceRegression AnalysisRetrospective Studies

Identifiers

PMID21228825
OpenAlexW2078154845

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.