ArticleAmerican journal of epidemiology2011
Overweight adults may have the lowest mortality--do they have the best health?
Article in American journal of epidemiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Behavioral Lifestyles and Survival: A Meta-Analysis.Frontiers in psychology · 2021Pooled it
- Association between daily level of objective physical activity and C-Reactive protein in a representative national sample of adults with self-reported diagnosed arthritis or fibromyalgia.Rheumatology international · 2020Observational
- Potential Health Implications and Health Cost Reductions of Transit-Induced Physical Activity.Journal of transport & health · 2016Article
- Beliefs about causes of weight gain, effective weight gain prevention strategies, and barriers to weight management in the Australian population.Health psychology and behavioral medicine · 2014Article
- Individual predictors of increased serum mesothelin in asbestos-exposed workers.Medical oncology (Northwood, London, England) · 2013Article
- Bodyweight, gender, and quality of life: a population-based longitudinal study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2012Article
- The association between obesity, cardiometabolic disease biomarkers, and innate immunity-related inflammation in Canadian adults.Diabetes, metabolic syndrome and obesity : targets and therapy · 2012Article
- Comparing years of healthy life, measured in 16 ways, for normal weight and overweight older adults.Journal of obesity · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Numerous recent studies have found that overweight adults experience lower overall mortality than those who are underweight, normal-weight, or obese. These highly publicized findings imply that overweight may be the optimal weight category for overall health via its association with longevity-a conclusion with important public health implications. In this study, the authors examined the association between body mass index (BMI; (weight (kg)/height (m)(2))) and 3 markers of health risks using a nationally representative sample of US adults aged 20-80 years (n = 9,255) from the National Health and Nutrition Examination Survey (2005-2008). Generalized additive models, a type of semiparametric regression model, were used to examine the relations between BMI and biomarkers of inflammation, metabolic function, and cardiovascular function (C-reactive protein, hemoglobin A(1c), and high density lipoprotein cholesterol, respectively). The association between BMI and each biomarker was monotonic, with higher BMI being consistently associated with worse health risk profiles at all ages, in contrast to the U-shaped relation between BMI and mortality. Prior results suggesting that the overweight BMI category corresponds to the lowest risk of mortality may not be generalizable to indicators of health risk.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.