ArticleThe American journal of clinical nutrition2011
Maternal vitamin D status during pregnancy and body composition and cardiovascular risk markers in Indian children: the Mysore Parthenon Study.
Article in The American journal of clinical nutrition, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 6 of them syntheses that pooled it.
What it found
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Who cites it
76 citing papers in PubMed, 6 syntheses or guidelines pooled it, 132 citations in OpenAlex.
- The Gestational Effects of Maternal Bone Marker Molecules on Fetal Growth, Metabolism and Long-Term Metabolic Health: A Systematic Review.International journal of molecular sciences · 2022Pooled it
- Pooled estimate of vitamin D deficiency among pregnant women in India: a systematic review and meta-analysis.Journal of health, population, and nutrition · 2021Pooled it
- Pooled it
- Is vitamin D deficiency a public health concern for low middle income countries? A systematic literature review.European journal of nutrition · 2019Pooled it
- Global summary of maternal and newborn vitamin D status - a systematic review.Maternal & child nutrition · 2016Pooled it
- Vitamin D during pregnancy and maternal, neonatal and infant health outcomes: a systematic review and meta-analysis.Paediatric and perinatal epidemiology · 2012Pooled it
- Maternal vitamin D supplementation in pregnancy and offspring outcomes: a double-blind randomized placebo-controlled trial.Journal of bone and mineral metabolism · 2017Trial
- Associations of umbilical cord vitamin D levels with childhood cardiometabolic risks: a longitudinal mother-child study.Frontiers in nutrition · 2026Article
- Perinatal Vitamin D Deficiency Enhances Brown Adipose Tissue Thermogenesis in Weanling Rats.International journal of molecular sciences · 2025Article
- Maternal Serum 25-Hydroxyvitamin D as a Possible Modulator of Fetal Adiposity: A Prospective Longitudinal Study.International journal of molecular sciences · 2025Article
- Role of Maternal Vitamin DJournal of the American Heart Association · 2025Article
- Maternal vitamin D status in relation to cardiometabolic risk factors in children from the Norwegian Environmental Biobank.PloS one · 2025Article
- Prenatal Vitamin D Levels Influence Growth and Body Composition until 11 Years in Boys.Nutrients · 2023Article
- Review
- The effect of maternal vitamin D deficiency during pregnancy on glycolipid metabolism of offspring rats and the improvement of vitamin D intervention after weaning.Frontiers in nutrition · 2023Article
- Maternal vitamin D status and risk of childhood overweight at 5 years of age in two Nordic cohort studies.Frontiers in nutrition · 2023Article
- Vitamin D deficiency in British South Asians, a persistent but avoidable problem associated with many health risks (including rickets, T2DM, CVD, COVID-19 and pregnancy complications): the case for correcting this deficiency.Endocrine connections · 2022Review
- Month-of-Birth Effect on Muscle Mass and Strength in Community-Dwelling Older Women: The French EPIDOS Cohort.Nutrients · 2022Article
- Early pregnancy vitamin D status is associated with blood pressure in children: an Odense Child Cohort study.The American journal of clinical nutrition · 2022Observational
- Maternal Vitamin D Deficiency in Mice Increases White Adipose Tissue Inflammation in Offspring.Cells · 2022Article
16 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
8 authors at 1 institution in 2 countries.
Funding
Abstract
backgroundMetabolic consequences of vitamin D deficiency have become a recent research focus. Maternal vitamin D status is thought to influence musculoskeletal health in children, but its relation with offspring metabolic risk is not known.
objectiveWe aimed to examine the association between maternal vitamin D status and anthropometric variables, body composition, and cardiovascular risk markers in Indian children.
designSerum 25-hydroxyvitamin D [25(OH)D] concentrations were measured at 28-32 wk gestation in 568 women who delivered at Holdsworth Memorial Hospital, Mysore, India. Anthropometric variables, glucose and insulin concentrations, blood pressure, and fasting lipid concentrations were measured in the offspring at 5 and 9.5 y of age. Muscle-grip strength was measured by using a hand-held dynamometer at age 9.5 y. Arm-muscle area was calculated as a measure of muscle mass. Fasting insulin resistance was calculated by using the homeostasis model assessment equation.
resultsSixty-seven percent of women had vitamin D deficiency [serum 25(OH)D concentration <50 nmol/L]. At ages 5 and 9.5 y, children born to vitamin D-deficient mothers had smaller arm-muscle area in comparison with children born to mothers without deficiency (P < 0.05). There was no difference in grip strength between offspring of women with and without vitamin D deficiency. At 9.5 y, children of vitamin D-deficient mothers had higher fasting insulin resistance than did children of nondeficient women (P = 0.04). There were no associations between maternal vitamin D status and other offspring risk factors at either age.
conclusionIntrauterine exposure to low 25(OH)D concentrations is associated with less muscle mass and higher insulin resistance in children.
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Registered trials
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