ArticleCardiovascular diabetology2011
Relationship between intima-media thickness of the common carotid artery and arterial stiffness in subjects with and without type 2 diabetes: a case-series report.
Article in Cardiovascular diabetology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 47 citations in OpenAlex.
- A randomised study of the impact of the SGLT2 inhibitor dapagliflozin on microvascular and macrovascular circulation.Cardiovascular diabetology · 2017 · on this mapTrial
- Effects of weight loss and insulin reduction on arterial stiffness in the SAVE trial.Cardiovascular diabetology · 2012Trial
- Detrimental effects of physical inactivity on peripheral and brain vasculature in humans: Insights into mechanisms, long-term health consequences and protective strategies.Frontiers in physiology · 2022Review
- Dyslipidemia, Insulin Resistance, Ectopic Lipid Accumulation, and Vascular Function in Resistance to Thyroid Hormone β.The Journal of clinical endocrinology and metabolism · 2021Article
- Effect of present versus previous smoking on non-invasive haemodynamics.Scientific reports · 2018Article
- Relationship between increased carotid artery stiffness and idiopathic subjective tinnitus: methodological issues.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2017Article
- The relationship between HbA₁c and ultrasound plaque textures in atherosclerotic patients.Cardiovascular diabetology · 2016Article
- Ambulatory arterial stiffness index is associated with impaired left atrial mechanical functions in hypertensive diabetic patients: A speckle tracking study.Anatolian journal of cardiology · 2015Article
- Ambulatory arterial stiffness index is not associated with magnetic resonance imaging markers of cerebral small vessel disease in lacunar stroke patients.Journal of clinical hypertension (Greenwich, Conn.) · 2015Article
- Evaluation of carotid artery elasticity changes in patients with type 2 diabetes.Cardiovascular diabetology · 2014Article
- Arterial stiffness, fatty liver and the presence of coronary artery calcium in a large population cohort.Cardiovascular diabetology · 2013Article
- Effect of vitamin D on aortic remodeling in streptozotocin-induced diabetes.Cardiovascular diabetology · 2012Article
- Using the spring constant method to analyze arterial elasticity in type 2 diabetic patients.Cardiovascular diabetology · 2012Article
- Insulin resistance increases the occurrence of new cardiovascular events in patients with manifest arterial disease without known diabetes. the SMART study.Cardiovascular diabetology · 2011Article
- Arterial indices and serum cystatin C level in individuals with occupational wide band noise exposure.Noise & healthArticle
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Authors and funding
8 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundWe examined the relationship between the intima-media thickness of the common carotid artery (CCA-IMT) and arterial stiffness, assessed by pulse wave velocity (PWV), the ambulatory arterial stiffness index (AASI) and the augmentation index (AIx) in subjects with and without type 2 diabetes.
methodsA case-series study was made in 366 patients (105 diabetics and 261-non-diabetics). Ambulatory blood pressure monitoring was performed on a day of standard activity with the SpaceLabs 90207 system. AASI was calculated as "1-slope" from the within-person regression of diastolic-on-systolic ambulatory blood pressure readings. PWV and AIx were measured with the SphygmoCor system, and a Sonosite Micromax ultrasound unit was used for automatic measurements of CCA-IMT.
resultsPWV, AASI and CCA-IMT were found to be greater in diabetic patients, while no differences in AIx were observed between the two groups. CCA-IMT was independently correlated to the three measures of arterial stiffness in both groups. We found an increase in CCA-IMT of 0.40, 0.24 and 0.36 mm in diabetics, and of 0.48, 0.17 and 0.55 mm in non-diabetics for each unit increase in AASI, AIx and PWV. The variability of CCA-IMT was explained mainly by AASI, AIx and gender in diabetic patients, and by age, gender, AASI and PWV in non-diabetic patients.
conclusionsCCA-IMT showed a positive correlation to PWV, AASI and AIx in subjects with and without type 2 diabetes. However, when adjusting for age, gender and heart rate, the association to PWV was lost in diabetic patients, in the same way as the association to Alx in non-diabetic patients. The present study demonstrates that the three measures taken to assess arterial stiffness in clinical practice are not interchangeable, nor do they behave equally in all subjects.
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