ReviewAnnual review of medicine2011
Therapeutic potential of lung epithelial progenitor cells derived from embryonic and induced pluripotent stem cells.
Review in Annual review of medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Bone Morphogenetic Protein 4 (BMP4) Enhances the Differentiation of Human Induced Pluripotent Stem Cells into Limbal Progenitor Cells.Current issues in molecular biology · 2021Article
- Stem cell therapy in chronic obstructive pulmonary disease. How far is it to the clinic?American journal of stem cells · 2018Review
- Stimulatory Secretions of Airway Epithelial Cells Accelerate Early Repair of Tracheal Epithelium.Scientific reports · 2017Article
- High-Throughput Toxicity and Phenotypic Screening of 3D Human Neural Progenitor Cell Cultures on a Microarray Chip Platform.Stem cell reports · 2016Article
- Aerosol generation and characterization of multi-walled carbon nanotubes exposed to cells cultured at the air-liquid interface.Particle and fibre toxicology · 2016Review
- Stem Cell-Based Therapy in Idiopathic Pulmonary Fibrosis.Stem cell reviews and reports · 2015Review
- Derivation of Endodermal Progenitors From Pluripotent Stem Cells.Journal of cellular physiology · 2015Review
- Evaluating Electroporation and Lipofectamine Approaches for Transient and Stable Transgene Expressions in Human Fibroblasts and Embryonic Stem Cells.Cell journal · 2015Article
- Clinical potentials of human pluripotent stem cells in lung diseases.Clinical and translational medicine · 2014Review
- The rabbit as a model for studying lung disease and stem cell therapy.BioMed research international · 2013Review
- Lung stem and progenitor cells.Respiration; international review of thoracic diseases · 2013Review
- Regenerative pulmonary medicine: potential and promise, pitfalls and challenges.European journal of clinical investigation · 2012Review
- Specimen collection for induced pluripotent stem cell research: harmonizing the approach to informed consent.Stem cells translational medicine · 2012Article
- Review
- Article
- In Vitro Generation of Red Blood Cells from Stem Cell and Targeted Therapy.Cell transplantationArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Embryonic stem (ES) cells derived from preimplantation blastocysts and induced pluripotent stem (iPS) cells generated from somatic cell sources are pluripotent and capable of indefinite expansion in vitro. They provide a possible unlimited source of cells that could be differentiated into lung progenitor cells for potential clinical use in pulmonary regenerative medicine. Because of inherent difficulties in deriving endodermal cells from undifferentiated cell cultures, applications using lung epithelial cells derived from ES and iPS cells have lagged behind similar efforts devoted to other tissues, such as the heart and spinal cord. However, during the past several years, significant advances in culture, differentiation, and purification protocols, as well as in bioengineering methodologies, have fueled enthusiasm for the development of stem cell-based lung therapeutics. This article provides an overview of recent research achievements and discusses future technical challenges that must be met before the promise of stem cell applications for lung disease can be realized.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.