Evidence map›Paper›PMID 21226585›Full record

ArticleThe New England journal of medicine2011

Reprogramming fibroblasts into cardiomyocytes.

Charles E Murry, William T Pu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The New England journal of medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Reprogramming for cardiac regeneration.Global cardiology science & practice · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Charles E MurryDepartment of Pathology, Center for Cardiovascular Biology, Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, USA.
William T Pu

Funding

Microenvironmental control of progenitors in organ dysfunction and repairU01HL100401 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI OLSON, ERIC N, SCHNEIDER, JAY W · 2009 to 2015
$8.3M
Cell-Based Cardiac RepairR01HL084642 · NHLBI · UNIVERSITY OF WASHINGTON · PI MURRY, CHARLES E · 2007 to 2014
$4.9M
Epicardial progenitors in the developing and postnatal heartR01HL094683 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI PU, WILLIAM TSWENCHING · 2009 to 2016
$3.7M
YAP1 Regulation of cardiomyocyte proliferation, function, and regenerationR01HL116461 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI PU, WILLIAM TSWENCHING · 2013 to 2017
$2.6M
Regulation of Heart Function by a Gata4-Fog2 transcriptional complexR01HL095712 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI PU, WILLIAM TSWENCHING · 2010 to 2013
$1.7M
Characterization of Cardiac Progenitors Derived from 22q11-deleted PatientsRC1HL099618 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI CHIEN, KENNETH R, PU, WILLIAM TSWENCHING · 2009 to 2010
$997k
HAND GENES IN CARDIAC DEVELOPMENTK08HL004387 · NHLBI · CHILDREN'S HOSPITAL BOSTON · PI PU, WILLIAM TSWENCHING · 2000 to 2004
$619k
Genome-wide discovery of alternative splicing in human heart failureR21HL089417 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI PU, WILLIAM TSWENCHING · 2007 to 2009
$600k
NHLBI NIH HHS K08 HL004387NHLBI NIH HHS R01 HL084642NHLBI NIH HHS R01 HL094683NHLBI NIH HHS R01 HL095712NHLBI NIH HHS R01 HL116461NHLBI NIH HHS R21 HL089417NHLBI NIH HHS RC1 HL099618NHLBI NIH HHS U01 HL100401
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cell DifferentiationTranscriptional ActivationAnimalsFibroblastsGenes, ReporterHeart FailureMiceMyocytes, CardiacTranscription FactorsTranscription Factors

Identifiers

PMID21226585
PMCPMC3639289

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.