ArticleLangmuir : the ACS journal of surfaces and colloids2011
Polymerized planar suspended lipid bilayers for single ion channel recordings: comparison of several dienoyl lipids.
Article in Langmuir : the ACS journal of surfaces and colloids, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Nanodomain Formation in Planar Supported Lipid Bilayers Composed of Fluid and Polymerized Dienoyl Lipids.Langmuir : the ACS journal of surfaces and colloids · 2019Article
- Surface Modification of Glass/PDMS Microfluidic Valve Assemblies Enhances Valve Electrical Resistance.ACS applied materials & interfaces · 2019Article
- Lipids in the cell: organisation regulates function.Cellular and molecular life sciences : CMLS · 2018Review
- Enhanced Temporal Resolution with Ion Channel-Functionalized Sensors Using a Conductance-Based Measurement Protocol.Analytical chemistry · 2017Article
- Bioinspired Assemblies and Plasmonic Interfaces for Electrochemical Biosensing.Journal of electroanalytical chemistry (Lausanne, Switzerland) · 2016Article
- Photopolymerization of Dienoyl Lipids Creates Planar Supported Poly(lipid) Membranes with Retained Fluidity.Langmuir : the ACS journal of surfaces and colloids · 2016Article
- Label-free detection and identification of protein ligands captured by receptors in a polymerized planar lipid bilayer using MALDI-TOF MS.Analytical and bioanalytical chemistry · 2015Article
- Decoding long nanopore sequencing reads of natural DNA.Nature biotechnology · 2014Article
- Decreased aperture surface energy enhances electrical, mechanical, and temporal stability of suspended lipid membranes.ACS applied materials & interfaces · 2013Article
- Photolithographic fabrication of microapertures with well-defined, three-dimensional geometries for suspended lipid membrane studies.Analytical chemistry · 2013Article
- Practical considerations for preparing polymerized phospholipid bilayer capillary coatings for protein separations.Analytica chimica acta · 2013Article
- Determination of pore sizes and relative porosity in porous nanoshell architectures using dextran retention with single monomer resolution and proton permeation.Analytical chemistry · 2012Article
- Synthesis of a Diverse Library of N,N-Dimethylamino Containing Monomers Appropriate as Lipid Head Groups.Tetrahedron letters · 2011Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
The stabilization of suspended planar lipid membranes, or black lipid membranes (BLMs), through polymerization of mono- and bis-functionalized dienoyl lipids was investigated. Electrical properties, including capacitance, conductance, and dielectric breakdown voltage, were determined for BLMs composed of mono-DenPC, bis-DenPC, mono-SorbPC, and bis-SorbPC both prior to and following photopolymerization, with diphytanoyl phosphocholine (DPhPC) serving as a control. Poly(lipid) BLMs exhibited significantly longer lifetimes and increased the stability of air-water transfers. BLM stability followed the order bis-DenPC > mono-DenPC ≈ mono-SorbPC > bis-SorbPC. The conductance of bis-SorbPC BLMs was significantly higher than that of the other lipids, which is attributed to a high density of hydrophilic pores, resulting in relatively unstable membranes. The use of poly(lipid) BLMs as matrices for supporting the activity of an ion channel protein (IC) was explored using α-hemolysin (α-HL), a model IC. Characteristic i-V plots of α-HL were maintained following photopolymerization of bis-DenPC, mono-DenPC, and mono-SorbPC, demonstrating the utility of these materials for preparing more durable BLMs for single-channel recordings of reconstituted ICs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.