ArticleDepression and anxiety2011
The effects of latent variables in the development of comorbidity among common mental disorders.
Article in Depression and anxiety, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Common mental disorders and associated factors among Ethiopian prisoners: a systematic review and meta-analysis.Frontiers in psychiatry · 2023Pooled it
- Trial
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- Understanding general and specific associations between cyberbullying and psychopathological symptoms in adolescents: a latent dimensional approach.European child & adolescent psychiatry · 2024Article
- Early mortality after chemotherapy as a quality indicator-the leukemia perspective.Blood cancer journal · 2023Article
- The Impact of COVID-19 Related Social Distancing on Mental Health Outcomes: A Transdiagnostic Account.International journal of environmental research and public health · 2022Review
- Nature and prevalence of combinations of mental disorders and their association with excess mortality in a population-based cohort study.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2020Article
- Comorbidity within mental disorders: a comprehensive analysis based on 145 990 survey respondents from 27 countries.Epidemiology and psychiatric sciences · 2020Observational
- Treating depressive disorders with the Unified Protocol: A preliminary randomized evaluation.Journal of affective disorders · 2020Article
- Why Are Suicide Rates Increasing in the United States? Towards a Multilevel Reimagination of Suicide Prevention.Current topics in behavioral neurosciences · 2020Review
- Childhood generalized specific phobia as an early marker of internalizing psychopathology across the lifespan: results from the World Mental Health Surveys.BMC medicine · 2019Article
- The General Psychopathology Factor: Structural Stability and Generalizability to Within-Individual Changes.Frontiers in psychiatry · 2019Article
- The cross-national structure of mental disorders: results from the World Mental Health Surveys.Psychological medicine · 2018Article
- Exploring the Incorporation of a Positive Psychology Component in a Cognitive Behavioral Internet-Based Program for Depressive Symptoms. Results Throughout the Intervention Process.Frontiers in psychology · 2018Article
- Stress responsivity and the structure of common mental disorders: Transdiagnostic internalizing and externalizing dimensions are associated with contrasting stress appraisal biases.Journal of abnormal psychology · 2016Article
- Beyond comorbidity: Toward a dimensional and hierarchical approach to understanding psychopathology across the life span.Development and psychopathology · 2016Article
- Pediatric-Onset and Adult-Onset Separation Anxiety Disorder Across Countries in the World Mental Health Survey.The American journal of psychiatry · 2015Article
- Latent variable and network models of comorbidity: toward an empirically derived nosology.Social psychiatry and psychiatric epidemiology · 2015Article
Corrections and comments
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12 authors.
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Abstract
backgroundAlthough numerous studies have examined the role of latent predispositions to internalizing and externalizing disorders in the structure of comorbidity among common mental disorders, none examined latent predispositions in predicting development of comorbidity.
methodsA novel method was used to study the role of latent variables in the development of comorbidity among lifetime DSM-IV disorders in the National Comorbidity Surveys. Broad preliminary findings are briefly presented to describe the method. The method used survival analysis to estimate time-lagged associations among 18 lifetime DSM-IV anxiety, mood, behavior, and substance disorders. A novel estimation approach examined the extent to which these predictive associations could be explained by latent canonical variables representing internalizing and externalizing disorders.
resultsConsistently significant positive associations were found between temporally primary and secondary disorders. Within-domain time-lagged associations were generally stronger than between-domain associations. The vast majority of associations were explained by a model that assumed mediating effects of latent internalizing and externalizing variables, although the complexity of this model differed across samples. A number of intriguing residual associations emerged that warrant further investigation.
conclusionsThe good fit of the canonical model suggests that common causal pathways account for most comorbidity among the disorders considered. These common pathways should be the focus of future research on the development of comorbidity. However, the existence of several important residual associations shows that more is involved than simple mediation. The method developed to carry out these analyses provides a unique way to pinpoint these significant residual associations for subsequent focused study.
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