Evidence map›Paper›PMID 21225849›Full record

ReviewDepression and anxiety2011

Transitional and translational studies of risk for anxiety.

B J Casey, Erika J Ruberry, Victoria Libby, Charles E Glatt, Todd Hare, Fatima Soliman, Stephanie Duhoux, Helena Frielingsdorf, Nim Tottenham

Abstract readReview
In one paragraph

Review in Depression and anxiety, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Peer facilitation of emotion regulation in adolescence.Developmental cognitive neuroscience · 2023
    Review
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  10. Review
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  12. Monoamine-sensitive developmental periods impacting adult emotional and cognitive behaviors.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2015
    Review
  13. Article
  14. Article
  15. Article
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  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

B J CaseySackler Institute for Developmental Psychobiology, Weil Cornell Medical College, 1300 York Avenue, New York, NY 10065, USA. bjc2002@med.cornell.edu
Erika J Ruberry
Victoria Libby
Charles E Glatt
Todd Hare
Fatima Soliman
Stephanie Duhoux
Helena Frielingsdorf
Nim Tottenham

Funding

Weill Cornell/Rockefeller/Sloan-Kettering MST ProgramT32GM007739 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI HSU, KATHARINE C · 1985 to 2023
$51.1M
Role of conflict in memoryP50MH062196 · NIMH · PRINCETON UNIVERSITY · PI COHEN, JONATHAN D · 2000 to 2009
$18.9M
Statistical Genetics Core: Impact of BDNF Genotype and Stress on LearningP50MH079513 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI CASEY, BETTY J · 2008 to 2012
$9.4M
Predicting Heterogeneous Neurodevelopmental Outcomes in School-age Children with Early Caregiving AdversitiesR01MH091864 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MILHAM, MICHAEL PETER, TOTTENHAM, NIM · 2010 to 2022
$5.1M
Development of Basic Components of Decision MakingR01DA018879 · NIDA · WEILL MEDICAL COLL OF CORNELL UNIV · PI CASEY, BETTY J · 2004 to 2008
$2.0M
Brain Development Following InstitutionalizationR01MH073175 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI CASEY, BETTY J · 2004 to 2008
$2.0M
NIDA NIH HHS R01 DA018879NIGMS NIH HHS T32 GM007739NIMH NIH HHS 1R01 MH73175NIMH NIH HHS P50 MH062196NIMH NIH HHS P50 MH079513NIMH NIH HHS P50 MH62196NIMH NIH HHS R01 MH073175NIMH NIH HHS R01 MH091864
6 · The paper itself

Abstract

Adolescence reflects a period of increased rates of anxiety, depression, and suicide. Yet most teens emerge from this period with a healthy, positive outcome. In this article, we identify biological factors that may increase risk for some individuals during this developmental period by: (1) examining changes in neural circuitry underlying core phenotypic features of anxiety as healthy individuals transition into and out of adolescence; (2) examining genetic factors that may enhance the risk for psychopathology in one individual over another using translation from mouse models to human neuroimaging and behavior; and (3) examining the effects of early experiences on core phenotypic features of anxiety using human neuroimaging and behavioral approaches. Each of these approaches alone provides only limited information on genetic and environmental influences on complex human behavior across development. Together, they reflect an emerging field of translational developmental neuroscience in forming important bridges between animal models of neurodevelopmental and neuropsychiatric disorders.

Indexed as

Disease Models, AnimalPhenotypeAdolescentAdultAmygdalaAnimalsAnxiety DisordersBrain MappingChildExtinction, PsychologicalFacial ExpressionFearHumansMagnetic Resonance ImagingMiceNerve Net

Identifiers

PMID21225849
PMCPMC3070413

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.