Evidence map›Paper›PMID 21225470›Full record

ReviewCellular & molecular biology letters2011

Laminopathies: the molecular background of the disease and the prospects for its treatment.

Magdalena Zaremba-Czogalla, Magda Dubińska-Magiera, Ryszard Rzepecki

Abstract readReview
In one paragraph

Review in Cellular & molecular biology letters, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. A Muscle Hybrid Promoter as a Novel Tool for Gene Therapy.Molecular therapy. Methods & clinical development · 2019
    Article
  9. Article
  10. Review
  11. Review
  12. Invertebrate models of lamin diseases.Nucleus (Austin, Tex.) · 2018
    Review
  13. Article
  14. Article
  15. Genetics of Lipodystrophy.Endocrinology and metabolism clinics of North America · 2017
    Review
  16. Lamin A/C Cardiomyopathies: Current Understanding and Novel Treatment Strategies.Current treatment options in cardiovascular medicine · 2017
    Review
  17. Article
  18. Article
  19. Review
  20. Advances in basic and clinical research in laminopathies.Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology · 2013
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Magdalena Zaremba-CzogallaLaboratory of Nuclear Proteins, Faculty of Biotechnology, University of Wrocław, ul. Przybyszewskiego 63/77, 51-148, Wroclaw, Poland.
Magda Dubińska-Magiera
Ryszard Rzepecki

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Laminopathies are rare human degenerative disorders with a wide spectrum of clinical phenotypes, associated with defects in the main protein components of the nuclear envelope, mostly in the lamins. They include systemic disorders and tissue-restricted diseases. Scientists have been trying to explain the pathogenesis of laminopathies and find an efficient method for treatment for many years. In this review, we discuss the current state of knowledge about laminopathies, the molecular mechanisms behind the development of particular phenotypes, and the prospects for stem cell and/or gene therapy treatments.

Indexed as

Genetic Diseases, InbornGenetic TherapyHumansLaminsLipodystrophyMuscular DiseasesNuclear EnvelopeProgeriaLamins

Identifiers

PMID21225470
PMCPMC6275778

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.