Evidence map›Paper›PMID 21224011›Full record

ArticleBiology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation2011

National Cancer Institute's First International Workshop on the Biology, Prevention, and Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation: summary and recommendations from the organizing committee.

Michael R Bishop, Edwin P Alyea, Mitchell S Cairo, J H Frederik Falkenburg, Carl H June, Nicolaus Kröger, Richard F Little, Jeffrey S Miller, Steven Z Pavletic, David L Porter and 6 more

Open access · hybridAbstract read
In one paragraph

Article in Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 40 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. The role of second transplants for leukemia.Best practice & research. Clinical haematology · 2016
    Review
  9. Article
  10. Maintenance Therapy with Decitabine after Allogeneic Stem Cell Transplantation for Acute Myelogenous Leukemia and Myelodysplastic Syndrome.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2015
    Article
  11. Article
  12. Survival of patients with acute myeloid leukemia relapsing after allogeneic hematopoietic cell transplantation: a center for international blood and marrow transplant research study.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2015
    Observational
  13. Increasing chimerism after allogeneic stem cell transplantation is associated with longer survival time.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2014
    Article
  14. Factors predictive of relapse of acute leukemia in children after allogeneic hematopoietic cell transplantation.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2014
    Article
  15. Outcome and prognostic factors for patients who relapse after allogeneic hematopoietic stem cell transplantation.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2013
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Outcomes of allogeneic hematopoietic cell transplantation for adolescent and young adults compared with children and older adults with acute myeloid leukemia.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 11 institutions in 3 countries.

Michael R BishopExperimental Transplantation and Immunology Branch, National Cancer Institute, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892, USA. mbishop@mail.nih.gov
Edwin P Alyea
Mitchell S Cairo
J H Frederik Falkenburg
Carl H June
Nicolaus Kröger
Richard F Little
Jeffrey S Miller
Steven Z Pavletic
David L Porter
Stanley R Riddell
Koen van Besien
Alan S Wayne
Daniel J Weisdorf
Roy S Wu
Sergio Giralt
National Institutes of Health · USNational Cancer Institute · USUniversity of Minnesota · USUniversity of Pennsylvania · USDana-Farber Cancer Institute · USFred Hutch Cancer Center · USLeiden University Medical Center · NLMemorial Sloan Kettering Cancer Center · USMorgan Stanley Children's Hospital · USUniversity Medical Center Hamburg-Eppendorf · DEUniversity of Chicago · US

Funding

Experimental Therapeutics of Pediatric Hematopoietic MalignanciesZICSC010353 · NCI · DIVISION OF CLINICAL SCIENCES - NCI · PI WAYNE, ALAN S · 2009 to 2013
$4.9M
Relapse after Allogeneic Hematopoietic Stem Cell TransplantationZIABC011239 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI BISHOP, MICHAEL R · 2009 to 2011
$544k
Intramural NIH HHS ZIA BC011239
6 · The paper itself

Abstract

The National Cancer Institute's First International Workshop on the Biology, Prevention, and Treatment of Relapse after Allogeneic Hematopoietic Stem Cell Transplantation was organized and convened to identify, prioritize, and coordinate future research activities related to relapse after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Each of the Workshop's 6 Working Committees has published individual reports of ongoing basic, translational, and clinical research and recommended areas for future research related to the areas of relapse biology, epidemiology, prevention, and treatment. This document summarizes each committee's recommendations and suggests 3 major initiatives for a coordinated research effort to address the problem of relapse after allo-HSCT: (1) to establish multicenter correlative and clinical trial networks for basic/translational, epidemiologic, and clinical research; (2) to establish a network of biorepositories for the collection of samples before and after allo-HSCT to aid in laboratory and clinical studies; and (3) to further refine, implement, and study the Workshop-proposed definitions for disease-specific response and relapse and recommendations for monitoring of minimal residual disease. These recommendations, in coordination with ongoing research initiatives and transplantation organizations, provide a research framework to rapidly and efficiently address the significant problem of relapse after allo-HSCT.

Indexed as

EducationHematopoietic Stem Cell TransplantationClinical Trials as TopicHematologic NeoplasmsHumansMonitoring, PhysiologicMulticenter Studies as TopicNational Cancer Institute (U.S.)Neoplasm, ResidualPractice Guidelines as TopicRecurrenceTransplantation, HomologousUnited States

Identifiers

PMID21224011
PMCPMC3102296
OpenAlexW2128499479

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.