ArticleInternational urogynecology journal2011
Site-specific prolapse surgery. II. Vaginal paravaginal repair augmented with either synthetic mesh or remodelling xenograft.
Article in International urogynecology journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed, 16 citations in OpenAlex.
- Feasibility and outcome of vaginal paravaginal repair using the Capio suture-capturing device.International urogynecology journal · 2012Trial
- Use of surgisis for treatment of anterior and posterior vaginal prolapse.Obstetrics and gynecology international · 2012Article
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introduction and hypothesisThis study aims to answer the question, "Does tissue augmentation improve the mechanical repair of displacement cystourethrocoele?"
methodsA retrospective cohort study comparing 108 bridging graft vaginal paravaginal repairs (89 tissue-inductive xenografts and 19 polypropylene mesh) to 59 native tissue historical controls was conducted. Main outcome measures were same-site prolapse recurrence and time to failure. Initial reliability was evaluated by chi-squared test, 10-year durability by Kaplan-Meier survival analysis and risk factors by Cox regression.
resultsLate recurrence was 17.7% lower with augmentation (logrank test χ (2) = 8.4, p value = 0.0038 < 0.05, adjusted regression analysis χ (2) = 2.94; p value = 0.0866 <0.10), implicating collagen degeneration in repair failure.
conclusionsRebuilding the pubocervical septum, from arcus to arcus and pubic ramus to pericervical ring, satisfies the mechanical but not the metabolic hernia principles. Bridging grafts simplify technical repair (reducing prolapse persistence from 10.2% to 4.6%), and also rejuvenate adjacent connective tissue (reducing late recurrence from 22.6% to 4.9%).
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