ArticleEuropean journal of applied physiology2011
Effects of static contraction and cold stimulation on cardiovascular autonomic indices, trapezius blood flow and muscle activity in chronic neck-shoulder pain.
Article in European journal of applied physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 65 citations in OpenAlex.
- Acute Blood Pressure Response to Different Types of Isometric Exercise: A Systematic Review with Meta-Analysis.Reviews in cardiovascular medicine · 2023Pooled it
- Systematic review of quantitative imaging biomarkers for neck and shoulder musculoskeletal disorders.BMC musculoskeletal disorders · 2017Pooled it
- Vagally Mediated Heart Rate Variability and Mood States in Patients with Chronic Pain Receiving Prolonged Expiration Regulated Breathing: A Randomized Controlled Trial.Applied psychophysiology and biofeedback · 2024Trial
- The effect of spinal manipulative therapy and home stretching exercises on heart rate variability in patients with persistent or recurrent neck pain: a randomized controlled trial.Chiropractic & manual therapies · 2021Trial
- Investigation of Effects of Ultrasound Therapy on Trapezius Muscle Stiffness and Choroidal Blood Flow Velocity.Muscles (Basel, Switzerland) · 2026Article
- Assessing the viability of heart rate variability as an objective and comprehensive indicator of chronic non-specific neck pain.PloS one · 2025Article
- The Relationship between Heart Rate Variability, Pain Intensity, Pain Catastrophizing, Disability, Quality of Life and Range of Cervical Motion in Patients with Chronic Non-Specific Neck Pain: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2024Article
- Relation between heart rate variability and spectral analysis of electroencephalogram in chronic neuropathic pain patients.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2024Article
- Association of autonomic regulation with pain and disability in patients with chronic neck pain: a systematic review.Revista da Associacao Medica Brasileira (1992) · 2024Article
- Article
- Analysis of Physiological Responses during Pain Induction.Sensors (Basel, Switzerland) · 2022Article
- The autonomic nervous system: A potential link to the efficacy of acupuncture.Frontiers in neuroscience · 2022Review
- Compression at Myofascial Trigger Point on Chronic Neck Pain Provides Pain Relief through the Prefrontal Cortex and Autonomic Nervous System: A Pilot Study.Frontiers in neuroscience · 2017Article
- Effects of concurrent physical and cognitive demands on muscle activity and heart rate variability in a repetitive upper-extremity precision task.European journal of applied physiology · 2016Article
- Short- and long-term reliability of heart rate variability indices during repetitive low-force work.European journal of applied physiology · 2015Article
- Long-Term Monitoring of Physical Behavior Reveals Different Cardiac Responses to Physical Activity among Subjects with and without Chronic Neck Pain.BioMed research international · 2015Article
- Consistent interindividual increases or decreases in muscle sympathetic nerve activity during experimental muscle pain.Experimental brain research · 2014Article
- Oxygenation and hemodynamics do not underlie early muscle fatigue for patients with work-related muscle pain.PloS one · 2014Article
- Changes in physical activity and heart rate variability in chronic neck-shoulder pain: monitoring during work and leisure time.International archives of occupational and environmental health · 2014Article
- Heart rate variability in sciatica patients referred to spine surgery: a case control study.BMC musculoskeletal disorders · 2013Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of the present study was to investigate reactions in trapezius muscle blood flow (MBF), muscle activity, heart rate variability (HRV) and systemic blood pressure (BP) to autonomic tests in subjects with chronic neck-shoulder pain and healthy controls. Changes in muscle activity and blood flow due to stress and unfavourable muscle loads are known underlying factors of work-related muscle pain. Aberration of the autonomic nervous system (ANS) is considered a possible mechanism. In the present study, participants (n = 23 Pain, n = 22 Control) performed autonomic tests which included a resting condition, static hand grip test (HGT) at 30% of maximal voluntary contraction, a cold pressor test (CPT) and a deep breathing test (DBT). HRV was analysed in time and frequency domains. MBF and muscle activity were recorded from the upper trapezius muscles using photoplethysmography and electromyography (EMG). The pain group showed reduced low frequency-HRV (LF) and SDNN during rest, as well as a blunted BP response and increased LF-HRV during HGT (∆systolic 22 mm Hg; ∆LF(nu) 27%) compared with controls (∆systolic 27; ∆LF(nu) 6%). Locally, the pain group had attenuated trapezius MBF in response to HGT (Pain 122% Control 140%) with elevated trapezius EMG following HGT and during CPT. In conclusion, only HGT showed differences between groups in systemic BP and HRV and alterations in local trapezius MBF and EMG in the pain group. Findings support the hypothesis of ANS involvement at systemic and local levels in chronic neck-shoulder pain.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.