Evidence map›Paper›PMID 21221659›Full record

ArticleJournal of anesthesia2011

The child with glutaric aciduria type I: anesthetic and perioperative management.

Adelais G Tsiotou, Anna Malisiova, Nikolaos Bouzelos, Dimitrios Velegrakis

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In one paragraph

Article in Journal of anesthesia, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Orthopaedic manifestations of glutaric acidemia Type 1.Journal of children's orthopaedics · 2020
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Adelais G TsiotouAnesthesiology Department, Children's Hospital P. & A. Kyriakou, Arkadias 19-21, 115 26 Athens, Greece. adeltsiotou@yahoo.gr
Anna Malisiova
Nikolaos Bouzelos
Dimitrios Velegrakis

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glutaric aciduria type I (GA-1) is an inborn error of metabolism caused by a deficiency of glutaryl-CoA dehydrogenase. It presents early in life, usually after an episode of fever, dehydration, infection or fasting, and results in metabolic decompensation and neurologic damage. We report the perioperative management of a 5-year-old boy admitted to the hospital for surgery because of neurogenic hip dislocation. Here we present the preoperative preparation, which focused on appropriate fluid administration and therapy intensification, as well as the safe anesthetic management with inhalation anesthesia and remifentanil, taking into consideration the mitochondrial basis of the disease. Furthermore, the role of postoperative care is emphasized in relation to stress response prophylaxis and the avoidance of complications related to the disorder.

Indexed as

Preoperative CareAmino Acid Metabolism, Inborn ErrorsAnesthesiaBrain Diseases, MetabolicChild, PreschoolGlutaryl-CoA DehydrogenaseHip DislocationHumansMalePostoperative CareGlutaryl-CoA Dehydrogenase

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.