Evidence map›Paper›PMID 21221600›Full record

ArticleHeart and vessels2011

Utility of myocardial fractional flow reserve for prediction of restenosis following sirolimus-eluting stent implantation.

Hideshi Ishii, Toru Kataoka, Yoshiki Kobayashi, Takara Tsumori, Hiroaki Takeshita, Ryo Matsumoto, Nobuyuki Shirai, Hiroki Nishioka, Takao Hasegawa, Shinji Nakata and 4 more

Abstract read
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Article in Heart and vessels, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Prognostic value of post-percutaneous coronary intervention diastolic pressure ratio.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2022
    Article
  3. Validation of novel 3-dimensional quantitative coronary angiography based software to calculate fractional flow reserve post stenting.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2021
    Article
  4. Review
  5. Article
  6. A promising carbon-11-labeled sphingosine-1-phosphate receptor 1-specific PET tracer for imaging vascular injury.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Hideshi IshiiDepartment of Cardiology, Higashisumiyoshi Morimoto Hospital, Osaka, Japan.
Toru Kataoka
Yoshiki Kobayashi
Takara Tsumori
Hiroaki Takeshita
Ryo Matsumoto
Nobuyuki Shirai
Hiroki Nishioka
Takao Hasegawa
Shinji Nakata
Yoshihisa Shimada
Shoichi Ehara
Takashi Muro
Minoru Yoshiyama

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drug-eluting stents reduce restenosis due to neointimal growth suppression. Considering long-term outcomes, it is both difficult and important to predict drug-eluting stent restenosis. Thus, this study was designed to examine the utility of myocardial fractional flow reserve (FFR) as a predictor of sirolimus-eluting stent (SES) restenosis. Thirty-three patients (35 lesions) were enrolled. Upon completion of SES implantation, FFR was obtained under hyperemia. At 8 months of follow-up, coronary angiography revealed that five lesions had restenosis. Percent diameter stenosis (restenosis 68.7 ± 12.8% vs. non-restenosis 68.7 ± 12.4%, p = 0.78) and lesion length (restenosis 15.8 ± 9.4 mm vs. non-restenosis 14.4 ± 9.2 mm, p = 0.60) were similar. At post-intervention, percent diameter stenosis (restenosis 16.4 ± 6.1% vs. non-restenosis 14.0 ± 7.4%, p = 0.48) and minimum stent area (restenosis 6.01 ± 1.08 mm2 vs. non-restenosis 6.27 ± 1.85 mm2, p = 0.92) were also equivalent. However, proximal edge lumen area was smaller (restenosis 4.24 ± 1.40 mm2 vs. non-restenosis 7.73 ± 2.64 mm2, p = 0.004) and FFR was lower in the restenosis group (restenosis 0.81 ± 0.12 vs. non-restenosis 0.92 ± 0.06, p = 0.029). SES patients with restenosis had a lower FFR post stent deployment, suggesting the decreased FFR may be a useful predictor for SES restenosis.

Indexed as

Drug-Eluting StentsFractional Flow Reserve, MyocardialAgedAngioplasty, Balloon, CoronaryCardiovascular AgentsChi-Square DistributionCoronary AngiographyCoronary Artery DiseaseCoronary StenosisFemaleHumansJapanLogistic ModelsMaleMiddle AgedOdds RatioCardiovascular AgentsSirolimus

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Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.