Evidence map›Paper›PMID 21221581›Full record

ArticleWorld journal of surgery2011

A primer on a hepatocellular carcinoma bioresource bank using the cancer genome atlas guidelines: practical issues and pitfalls.

N Thao T Nguyen, Ron T Cotton, Theresa R Harring, Jacfranz J Guiteau, Marie-Claude Gingras, David A Wheeler, Christine A O'Mahony, Richard A Gibbs, F Charles Brunicardi, John A Goss

Abstract read
In one paragraph

Article in World journal of surgery, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

N Thao T NguyenMichael E. DeBakey Department of Surgery, Baylor College of Medicine, 1709 Dryden Road, Suite #1500, BCM390, Houston, TX 77030, USA.
Ron T Cotton
Theresa R Harring
Jacfranz J Guiteau
Marie-Claude Gingras
David A Wheeler
Christine A O'Mahony
Richard A Gibbs
F Charles Brunicardi
John A Goss
Baylor College of Medicine · USBaylor Genetics · US

Funding

The Human Genome Sequencing CenterU54HG003273 · NHGRI · BAYLOR COLLEGE OF MEDICINE · PI GIBBS, RICHARD A · 2004 to 2015
$341.3M
A Microbial Genome Reference Platform for MetagenomicsU54HG004973 · NHGRI · BAYLOR COLLEGE OF MEDICINE · PI GIBBS, RICHARD A, HIGHLANDER, SARAH KATHERINE · 2009 to 2010
$1.8M
NHGRI NIH HHS U54 HG003273NHGRI NIH HHS U54-HG003273NHGRI NIH HHS U54-HG004973
6 · The paper itself

Abstract

backgroundSince the advent of the human genome, the era of personalized genomic medicine is indisputably in progress.

methodsIn an effort to contribute to the evolving knowledge of genomic medicine, we have aimed directly at building a bioresource bank for hepatocellular carcinoma. This tumor bank is based on the rigorous guidelines set forth by the National Cancer Institute, and it offers analytes to help elucidate the mechanisms of progression from cirrhosis to malignancy, risk factors for recurrence, and applicability of current treatment options to a diverse group of people.

conclusionsSurgeons have a privileged position between patients (and their cancer) and the benches of basic science. Thus, we offer a primer based on our own experiences, from which surgeons may take elements to build their own bioresource bank for use in collaboration with others. We highlight some practicalities and pitfalls that could be overlooked, as well as a discussion of possible solutions.

Indexed as

Guidelines as TopicNational Cancer Institute (U.S.)Carcinoma, HepatocellularCell Transformation, NeoplasticCooperative BehaviorDatabases, GeneticDatabases, Nucleic AcidDisease ProgressionForecastingGenetic Predisposition to DiseaseGenome, HumanHumansInterdisciplinary CommunicationLiverLiver CirrhosisLiver Neoplasms

Identifiers

PMID21221581
PMCPMC4083491
OpenAlexW2048437118

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.