ArticleLab on a chip2011
Tailorable integrated optofluidic filters for biomolecular detection.
Article in Lab on a chip, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 40 citations in OpenAlex.
- Recent Advancements in Nanophotonics for Optofluidics.Advances in physics: X · 2024Article
- Planar Optofluidic Integration of Ring Resonator and Microfluidic Channels.Micromachines · 2022Article
- A Critical Review on the Sensing, Control, and Manipulation of Single Molecules on Optofluidic Devices.Micromachines · 2022Review
- Optical trapping assisted label-free and amplification-free detection of SARS-CoV-2 RNAs with an optofluidic nanopore sensor.Biosensors & bioelectronics · 2021Article
- An integrated, optofluidic system with aligned optical waveguides, microlenses, and coupling prisms for fluorescence sensing.Journal of microelectromechanical systems : a joint IEEE and ASME publication on microstructures, microactuators, microsensors, and microsystems · 2020Article
- Optofluidic devices with integrated solid-state nanopores.Mikrochimica acta · 2016Article
- Liquid Core ARROW Waveguides: A Promising Photonic Structure for Integrated Optofluidic Microsensors.Micromachines · 2016Review
- Silicon on-chip bandpass filters for the multiplexing of high sensitivity photonic crystal microcavity biosensors.Applied physics letters · 2015Article
- Time encoded multicolor fluorescence detection in a microfluidic flow cytometer.Lab on a chip · 2012Article
- Optofluidics incorporating actively controlled micro- and nano-particles.Biomicrofluidics · 2012Article
- Tailoring the spectral response of liquid waveguide diagnostic platforms.Journal of biophotonics · 2012Review
- Enhancement of ARROW Photonic Device Performance via Thermal Annealing of PECVD-based SiOIEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics SocietyArticle
- Signal-to-noise Enhancement in Optical Detection of Single Viruses with Multi-spot Excitation.IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics SocietyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Spectral filtering is an essential component of biophotonic methods such as fluorescence and Raman spectroscopy. Predominantly utilized in bulk microscopy, filters require efficient and selective transmission or removal of signals at one or more wavelength bands. However, towards highly sensitive and fully self-contained lab-on-chip systems, the integration of spectral filters is an essential step. In this work, a novel optofluidic solution is presented in which a liquid-core optical waveguide both transports sample analytes and acts as an efficient filter for advanced spectroscopy. To this end, the wavelength dependent nature of interference-based antiresonant reflecting optical waveguide technology is exploited. An extinction of 37 dB, a narrow rejection band of only 2.5 nm and a free spectral range of 76 nm using three specifically designed dielectric layers are demonstrated. These parameters result in an 18.4-fold increase in the signal-to-noise ratio for on-chip fluorescence detection. In addition, liquid-core waveguide filters with three operating wavelengths were designed for Förster resonance energy transfer detection and demonstrated using doubly labeled oligonucleotides. Incorporation of high-performance spectral processing illustrates the power of the optofluidic concept where fluidic channels also perform optical functions to create innovative and highly integrated lab-on-chip devices.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.