Is microbial translocation a cause or consequence of HIV disease progression?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

19 citing papers in PubMed.

1. Systemic immune activation and microbial translocation in dual HIV/tuberculosis-infected subjects.The Journal of infectious diseases · 2013
   Trial
2. Detection of microbial translocation in HIV and SIV infection using the Limulus amebocyte lysate assay is masked by serum and plasma.PloS one · 2012
   Trial
3. T cell activation is insufficient to drive SIV disease progression.JCI insight · 2023
   Article
4. Monocyte Dysfunction, Activation, and Inflammation After Long-Term Antiretroviral Therapy in an African Cohort.The Journal of infectious diseases · 2019
   Article
5. Microbial Translocation Does Not Drive Immune Activation in Ugandan Children Infected With HIV.The Journal of infectious diseases · 2019
   Article
6. Antibiotic and Antiinflammatory Therapy Transiently Reduces Inflammation and Hypercoagulation in Acutely SIV-Infected Pigtailed Macaques.PLoS pathogens · 2016
   Article
7. Comparative Analysis of Immune Activation Markers of CD8Frontiers in immunology · 2016
   Article
8. Cognitive consequences of a sustained monocyte type 1 IFN response in HIV-1 infection.Current HIV research · 2014
   Review
9. The secretion of IL-22 from mucosal NKp44⁺ NK cells is associated with microbial translocation and virus infection in SIV/SHIV-infected Chinese macaques.Journal of immunology research · 2014
   Article
10. Gut Microbiota in HIV Infection: Implication for Disease Progression and Management.Gastroenterology research and practice · 2014
    Review
11. The majority of HIV type 1 DNA in circulating CD4+ T lymphocytes is present in non-gut-homing resting memory CD4+ T cells.AIDS research and human retroviruses · 2013
    Article
12. Liver stiffness is associated with monocyte activation in HIV-infected Ugandans without viral hepatitis.AIDS research and human retroviruses · 2013
    Article
13. HIV-1 induced bystander apoptosis.Viruses · 2012
    Review
14. Environmental enteropathy: critical implications of a poorly understood condition.Trends in molecular medicine · 2012
    Review
15. Enteropathies in the developing world: neglected effects on global health.The American journal of tropical medicine and hygiene · 2012
    Review
16. Relationship between microbial translocation and endothelial function in HIV infected patients.PloS one · 2012
    Article
17. The transhepatic endotoxin gradient is present despite liver cirrhosis and is attenuated after transjugular portosystemic shunt (TIPS).BMC gastroenterology · 2011
    Article
18. Strong viremia control in vaccinated macaques does not prevent gradual Th17 cell loss from central memory.Vaccine · 2011
    Article
19. Successful aging and the epidemiology of HIV.Clinical interventions in aging · 2011
    Review

Corrections and comments

• Comment on
  Microbial translocation correlates with the severity of both HIV-1 and HIV-2 infections.2010
• Comment on
  Persistent microbial translocation and immune activation in HIV-1-infected South Africans receiving combination antiretroviral therapy.2010

Authors and funding

3 authors.

Funding

Abstract

PubMed holds no abstract for this paper.

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