Evidence map›Paper›PMID 21220401›Full record

ArticlePediatrics2011

Recurrent fever syndromes in patients after recovery from Kawasaki syndrome.

Lori Broderick, Adriana H Tremoulet, Jane C Burns, John F Bastian, Hal M Hoffman

Abstract readCase Reports
In one paragraph

Article in Pediatrics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Kawasaki disease: a matter of innate immunity.Clinical and experimental immunology · 2016
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lori BroderickDepartment of Pediatrics, University of California San Diego and Rady Children’s Hospital, San Diego, California, USA. lbroderick@ucsd.edu
Adriana H Tremoulet
Jane C Burns
John F Bastian
Hal M Hoffman

Funding

Matrix Metalloproteinases in Kawasaki DiseaseK24HL074864 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BURNS, JANE C · 2004 to 2008
$526k
NHLBI NIH HHS K24 HL074864
6 · The paper itself

Abstract

The recurrence of fever in a child with a history of Kawasaki syndrome (KS) poses a dilemma for clinicians who must consider the possibility of recurrent KS. In this report we present the cases of 4 patients who presented with classical symptoms of KS, were successfully treated with intravenous immunoglobulin, and later experienced a reappearance of inflammatory symptoms in a pattern consistent with a recurrent fever syndrome. The association of these syndromes within the same patient suggests that some patients may have a genetic propensity toward altered immune responses and autoinflammatory syndromes. We propose that these 2 syndromes exist within a family of febrile disorders related to innate immune dysregulation.

Indexed as

Recovery of FunctionChild, PreschoolFemaleFeverHumansImmunoglobulins, IntravenousInfantMaleMucocutaneous Lymph Node SyndromeRecurrenceImmunoglobulins, Intravenous

Identifiers

PMID21220401
PMCPMC3025426

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.