ArticleProceedings of the National Academy of Sciences of the United States of America2011
The Drosophila Myc gene, diminutive, is a positive regulator of the Sex-lethal establishment promoter, Sxl-Pe.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Differential neuronal survival defines a novel axis of sexual dimorphism in the Drosophila brain.Cell genomics · 2026Article
- Spermless males fail to remedy the low fecundity of parthenogenetic females inmicroPublication biology · 2025Article
- High-affinity biomolecular interactions are modulated by low-affinity binders.NPJ systems biology and applications · 2024Article
- Myc suppresses male-male courtship in Drosophila.The EMBO journal · 2022Article
- Capturing the transcription factor interactome in response to sub-lethal insecticide exposure.Current research in insect science · 2021Article
- Diversity of Insect Sesquiterpenoid Regulation.Frontiers in genetics · 2020Review
- Sexual dimorphism of sleep regulated by juvenile hormone signaling in Drosophila.PLoS genetics · 2018Article
- Revisiting the Role of the Male-Specific Lethal Complex in the Sex Determination Decision ofGenetics · 2018Article
- Article
- Bombyx mori P-element Somatic Inhibitor (BmPSI) Is a Key Auxiliary Factor for Silkworm Male Sex Determination.PLoS genetics · 2017Article
- An interactive network of long non-coding RNAs facilitates the Drosophila sex determination decision.Biochimica et biophysica acta · 2014Article
- Article
- Myc function in Drosophila.Cold Spring Harbor perspectives in medicine · 2013Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
The binary switch gene Sex-lethal (Sxl) controls sexual identity in Drosophila. When activated, Sxl imposes female identity, whereas male identity ensues by default when the gene is off. The decision to activate Sxl is controlled by an X chromosome counting system that regulates the Sxl establishment promoter, Sxl-Pe. The counting system depends upon the twofold difference in the gene dose of a series of X-linked transcription factors or numerators. Because of this difference in dose, early female embryos express twice the amount of these transcription factors, and the cumulative action of these transcription factors turns on Sxl-Pe. Here we show that the Drosophila Myc gene diminutive is an X-linked numerator.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.