Evidence map›Paper›PMID 21217962›Full record

ArticleClinical and experimental otorhinolaryngology2010

Optimal continuous positive airway pressure level in korean patients with obstructive sleep apnea syndrome.

Ji Ho Choi, Eun Joong Kim, Kang Woo Kim, June Choi, Soon Young Kwon, Heung Man Lee, Tae Hoon Kim, Sang Hag Lee, Chol Shin, Seung Hoon Lee

Registry-linked trialAbstract read
In one paragraph

Article in Clinical and experimental otorhinolaryngology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07376343 (Comparative Study of CPAP Predictive Equations and In-laboratory Manual Titration in Thai Patients With Obstructive Sleep Apnea), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07376343 recruitingnot on this mapstarted 2026, after this paper: background citation

Comparative Study of CPAP Predictive Equations and In-laboratory Manual Titration in Thai Patients With Obstructive Sleep Apnea

TypeobservationalSponsorThammasat UniversityRan2026 to 2026Enrolled150ConditionsOSA - Obstructive Sleep ApneaArmsSleep test, Predictive equations of continuous positive airway pressure (CPAP)
3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Are there sex-related differences in therapeutic CPAP levels in adults undergoing in-laboratory titration?Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021
    Article
  7. Titration studies overestimate continuous positive airway pressure requirements in uncomplicated obstructive sleep apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021
    Article
  8. Article
  9. Review
  10. Upper airway anatomical balance contributes to optimal continuous positive airway pressure for Japanese patients with obstructive sleep apnea syndrome.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2014
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ji Ho ChoiDepartment of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine, Seoul, Korea.
Eun Joong Kim
Kang Woo Kim
June Choi
Soon Young Kwon
Heung Man Lee
Tae Hoon Kim
Sang Hag Lee
Chol Shin
Seung Hoon Lee

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this study was to investigate optimal continuous positive airway pressure (CPAP) level, to examine the factors affecting optimal CPAP level, and to develop a predictive equation for optimal CPAP level in Korean patients with obstructive sleep apnea syndrome (OSAS).

methodsA total of 202 patients with OSAS who underwent successful manual titration for CPAP treatment were included in this study. Correlations between the optimal CPAP level and baseline data including anthropometric and polysomnographic variables were analyzed. A predictive equation for optimal CPAP level was developed based on anthropometric and polysomonographic data.

resultsThe mean optimal CPAP level in 202 patients with OSAS was 7.8±2.3 cm H(2)O. The mean optimal CPAP level in the mild, moderate, and severe OSAS groups was 6.0±1.3, 7.4±1.9, and 9.1±2.1 cm H(2)O, respectively. The apneahypopnea index (AHI) (r=0.595, P<0.001), arousal index (r=0.542, P<0.001), minimal SaO(2) (r=-0.502, P<0.001), body mass index (BMI) (r=0.494, P<0.001), neck circumference (r=0.265, P<0.001), and age (r=-0.164, P=0.019) were significantly correlated with optimal CPAP level. The best predictive equation according to stepwise multiple linear regression analysis was: Optimal CPAP level (cm H(2)O)=0.681+(0.205×BMI)+(0.040×AHI). Forty-two percent of the variance in the optimal CPAP level was explained by this equation (R(2)=0.42, P<0.001).

conclusionA predictive equation for optimal CPAP level in Korean patients with OSAS was developed using AHI and BMI, which can be easily measured during the diagnostic process.

Indexed as

Body mass indexContinuous positive airway pressureObstructive sleep apnea syndromePolysomnography

Identifiers

PMID21217962
PMCPMC3010540

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.