Evidence map›Paper›PMID 21217757›Full record

ArticleNature genetics2011

Genome-wide association study of quantitative resistance to southern leaf blight in the maize nested association mapping population.

Kristen L Kump, Peter J Bradbury, Randall J Wisser, Edward S Buckler, Araby R Belcher, Marco A Oropeza-Rosas, John C Zwonitzer, Stephen Kresovich, Michael D McMullen, Doreen Ware and 2 more

Abstract read
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In one paragraph

Article in Nature genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 286 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
286citing papers in PubMed, 1 pooled it
36.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

286 citing papers in PubMed, 1 synthesis or guideline pooled it, 617 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Genetic Dissection and Functional Validation ofInternational journal of molecular sciences · 2026
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226 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Kristen L KumpDepartment of Crop Science, North Carolina State University, Raleigh, North Carolina, USA.
Peter J Bradbury
Randall J Wisser
Edward S Buckler
Araby R Belcher
Marco A Oropeza-Rosas
John C Zwonitzer
Stephen Kresovich
Michael D McMullen
Doreen Ware
Peter J Balint-Kurti
James B Holland
North Carolina State University · USCornell University · USAgricultural Research Service · USUnited States Department of Agriculture · USUniversity of Delaware · USUniversity of Missouri · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nested association mapping (NAM) offers power to resolve complex, quantitative traits to their causal loci. The maize NAM population, consisting of 5,000 recombinant inbred lines (RILs) from 25 families representing the global diversity of maize, was evaluated for resistance to southern leaf blight (SLB) disease. Joint-linkage analysis identified 32 quantitative trait loci (QTLs) with predominantly small, additive effects on SLB resistance. Genome-wide association tests of maize HapMap SNPs were conducted by imputing founder SNP genotypes onto the NAM RILs. SNPs both within and outside of QTL intervals were associated with variation for SLB resistance. Many of these SNPs were within or near sequences homologous to genes previously shown to be involved in plant disease resistance. Limited linkage disequilibrium was observed around some SNPs associated with SLB resistance, indicating that the maize NAM population enables high-resolution mapping of some genome regions.

Indexed as

Chromosome MappingChromosomes, PlantCrosses, GeneticEpistasis, GeneticGenes, PlantGenome-Wide Association StudyGenotypeHaplotypesImmunity, InnatePhysical Chromosome MappingPlant DiseasesPlant LeavesPolymorphism, Single NucleotideZea mays

Identifiers

PMID21217757
OpenAlexW2064881644

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.